Genetic and biochemical identification of a novel single-stranded DNA binding complex in Haloferax volcanii

Genetic and biochemical identification of a novel single-stranded DNA binding complex in Haloferax volcanii

Single-stranded DNA binding proteins play an essential role in DNA replication and repair. They use oligosaccharide-binding folds, a five-stranded ß-sheet coiled into a closed barrel, to bind to single-stranded DNA thereby protecting and stabilizing the DNA. In eukaryotes the single-strande...

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Bibliographic Details
Main Authors: Amy eStroud, Susan eLiddell, Thorsten eAllers
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-06-01
Series:Frontiers in Microbiology
Subjects:
Archaea
DNA Repair
Haloferax volcanii
Cdc48d
COG3390 RPA-associated protein
Protein overexpression
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2012.00224/full

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