Sensitivity to Antibiotics of Bacteria Exposed to Gamma Radiation Emitted from Hot Soils of the High Background Radiation Areas of Ramsar, Northern Iran
Background: Over the past several years our laboratories have investigated different aspects of the challenging issue of the alterations in bacterial susceptibility to antibiotics induced by physical stresses. Objective: To explore the bacterial susceptibility to antibiotics in samples of Salmonell...
Main Authors: | , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
National Iranian Oil Company (NIOC) Health Organization
2017-04-01
|
Series: | The International Journal of Occupational and Environmental Medicine |
Subjects: | |
Online Access: | http://www.theijoem.com/ijoem/index.php/ijoem/article/view/958 |
id |
doaj-cc56a9ca9d984b67826e403542faa7eb |
---|---|
record_format |
Article |
spelling |
doaj-cc56a9ca9d984b67826e403542faa7eb2020-11-25T01:32:30ZengNational Iranian Oil Company (NIOC) Health OrganizationThe International Journal of Occupational and Environmental Medicine2008-65202008-68142017-04-018280410.15171/ijoem.2017.958280Sensitivity to Antibiotics of Bacteria Exposed to Gamma Radiation Emitted from Hot Soils of the High Background Radiation Areas of Ramsar, Northern IranSeyed Mohammad Javad Mortazavi0Samira Zarei1Mohammad Taheri2Saeed Tajbakhsh3Seyed Alireza Mortazavi4Sahar Ranjbar5Fatemeh Momeni6Samaneh Masoomi7Leila Ansari8Mohammad Mehdi Movahedi9Shahram Taeb10Sina Zarei11Masood Haghani12Department of Diagnostic Imaging, Fox Chase Cancer Center, 333 Cottman Ave, Philadelphia, PA 19111, USA, and Ionizing and Non-ionizing Radiation Protection Research Center (INIRPRC), Shiraz University of Medical Sciences, Shiraz, IranDepartment of Microbiology and Parasitology, Faculty of Medicine, Bushehr University of Medical Sciences, Bushehr, IranDepartment of Microbiology, School of Medicine, Kerman University of Medical Sciences, Kerman, IranDepartment of Microbiology and Parasitology, Faculty of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran and The Persian Gulf Tropical Medicine Research Center, Bushehr University of Medical Sciences, Bushehr, IranIonizing and Non-ionizing Radiation Protection Research Center (INIRPRC), Shiraz University of Medical Sciences, Shiraz, IranMedical Physics Department, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IranMedical Physics Department, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IranMedical Physics Department, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IranMedical Physics Department, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IranMedical Physics and Medical Engineering Department, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IranIonizing and Non-ionizing Radiation Protection Research Center (INIRPRC), Shiraz University of Medical Sciences, Shiraz, IranVarastegan University of Medical Sciences, Shiraz, IranIonizing and Non-ionizing Radiation Protection Research Center (INIRPRC), Shiraz University of Medical Sciences, Shiraz, IranBackground: Over the past several years our laboratories have investigated different aspects of the challenging issue of the alterations in bacterial susceptibility to antibiotics induced by physical stresses. Objective: To explore the bacterial susceptibility to antibiotics in samples of Salmonella enterica subsp. enterica serovar Typhimurium (S. typhimurium), Staphylococcus aureus, and Klebsiella pneumoniae after exposure to gamma radiation emitted from the soil samples taken from the high background radiation areas of Ramsar, northern Iran. Methods: Standard Kirby-Bauer test, which evaluates the size of the zone of inhibition as an indicator of the susceptibility of different bacteria to antibiotics, was used in this study. Results: The maximum alteration of the diameter of inhibition zone was found for K. pneumoniae when tested for ciprofloxacin. In this case, the mean diameter of no growth zone in non-irradiated control samples of K. pneumoniae was 20.3 (SD 0.6) mm; it was 14.7 (SD 0.6) mm in irradiated samples. On the other hand, the minimum changes in the diameter of inhibition zone were found for S. typhimurium and S. aureus when these bacteria were tested for nitrofurantoin and cephalexin, respectively. Conclusion: Gamma rays were capable of making significant alterations in bacterial susceptibility to antibiotics. It can be hypothesized that high levels of natural background radiation can induce adaptive phenomena that help microorganisms better cope with lethal effects of antibiotics.http://www.theijoem.com/ijoem/index.php/ijoem/article/view/958MicrobiologyBackground radiationMicrobial sensitivity testsElectromagnetic radiationGamma raysHormesis |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Seyed Mohammad Javad Mortazavi Samira Zarei Mohammad Taheri Saeed Tajbakhsh Seyed Alireza Mortazavi Sahar Ranjbar Fatemeh Momeni Samaneh Masoomi Leila Ansari Mohammad Mehdi Movahedi Shahram Taeb Sina Zarei Masood Haghani |
spellingShingle |
Seyed Mohammad Javad Mortazavi Samira Zarei Mohammad Taheri Saeed Tajbakhsh Seyed Alireza Mortazavi Sahar Ranjbar Fatemeh Momeni Samaneh Masoomi Leila Ansari Mohammad Mehdi Movahedi Shahram Taeb Sina Zarei Masood Haghani Sensitivity to Antibiotics of Bacteria Exposed to Gamma Radiation Emitted from Hot Soils of the High Background Radiation Areas of Ramsar, Northern Iran The International Journal of Occupational and Environmental Medicine Microbiology Background radiation Microbial sensitivity tests Electromagnetic radiation Gamma rays Hormesis |
author_facet |
Seyed Mohammad Javad Mortazavi Samira Zarei Mohammad Taheri Saeed Tajbakhsh Seyed Alireza Mortazavi Sahar Ranjbar Fatemeh Momeni Samaneh Masoomi Leila Ansari Mohammad Mehdi Movahedi Shahram Taeb Sina Zarei Masood Haghani |
author_sort |
Seyed Mohammad Javad Mortazavi |
title |
Sensitivity to Antibiotics of Bacteria Exposed to Gamma Radiation Emitted from Hot Soils of the High Background Radiation Areas of Ramsar, Northern Iran |
title_short |
Sensitivity to Antibiotics of Bacteria Exposed to Gamma Radiation Emitted from Hot Soils of the High Background Radiation Areas of Ramsar, Northern Iran |
title_full |
Sensitivity to Antibiotics of Bacteria Exposed to Gamma Radiation Emitted from Hot Soils of the High Background Radiation Areas of Ramsar, Northern Iran |
title_fullStr |
Sensitivity to Antibiotics of Bacteria Exposed to Gamma Radiation Emitted from Hot Soils of the High Background Radiation Areas of Ramsar, Northern Iran |
title_full_unstemmed |
Sensitivity to Antibiotics of Bacteria Exposed to Gamma Radiation Emitted from Hot Soils of the High Background Radiation Areas of Ramsar, Northern Iran |
title_sort |
sensitivity to antibiotics of bacteria exposed to gamma radiation emitted from hot soils of the high background radiation areas of ramsar, northern iran |
publisher |
National Iranian Oil Company (NIOC) Health Organization |
series |
The International Journal of Occupational and Environmental Medicine |
issn |
2008-6520 2008-6814 |
publishDate |
2017-04-01 |
description |
Background: Over the past several years our laboratories have investigated different aspects of the challenging issue of the alterations in bacterial susceptibility to antibiotics induced by physical stresses.
Objective: To explore the bacterial susceptibility to antibiotics in samples of Salmonella enterica subsp. enterica serovar Typhimurium (S. typhimurium), Staphylococcus aureus, and Klebsiella pneumoniae after exposure to gamma radiation emitted from the soil samples taken from the high background radiation areas of Ramsar, northern Iran.
Methods: Standard Kirby-Bauer test, which evaluates the size of the zone of inhibition as an indicator of the susceptibility of different bacteria to antibiotics, was used in this study.
Results: The maximum alteration of the diameter of inhibition zone was found for K. pneumoniae when tested for ciprofloxacin. In this case, the mean diameter of no growth zone in non-irradiated control samples of K. pneumoniae was 20.3 (SD 0.6) mm; it was 14.7 (SD 0.6) mm in irradiated samples. On the other hand, the minimum changes in the diameter of inhibition zone were found for S. typhimurium and S. aureus when these bacteria were tested for nitrofurantoin and cephalexin, respectively.
Conclusion: Gamma rays were capable of making significant alterations in bacterial susceptibility to antibiotics. It can be hypothesized that high levels of natural background radiation can induce adaptive phenomena that help microorganisms better cope with lethal effects of antibiotics. |
topic |
Microbiology Background radiation Microbial sensitivity tests Electromagnetic radiation Gamma rays Hormesis |
url |
http://www.theijoem.com/ijoem/index.php/ijoem/article/view/958 |
work_keys_str_mv |
AT seyedmohammadjavadmortazavi sensitivitytoantibioticsofbacteriaexposedtogammaradiationemittedfromhotsoilsofthehighbackgroundradiationareasoframsarnortherniran AT samirazarei sensitivitytoantibioticsofbacteriaexposedtogammaradiationemittedfromhotsoilsofthehighbackgroundradiationareasoframsarnortherniran AT mohammadtaheri sensitivitytoantibioticsofbacteriaexposedtogammaradiationemittedfromhotsoilsofthehighbackgroundradiationareasoframsarnortherniran AT saeedtajbakhsh sensitivitytoantibioticsofbacteriaexposedtogammaradiationemittedfromhotsoilsofthehighbackgroundradiationareasoframsarnortherniran AT seyedalirezamortazavi sensitivitytoantibioticsofbacteriaexposedtogammaradiationemittedfromhotsoilsofthehighbackgroundradiationareasoframsarnortherniran AT saharranjbar sensitivitytoantibioticsofbacteriaexposedtogammaradiationemittedfromhotsoilsofthehighbackgroundradiationareasoframsarnortherniran AT fatemehmomeni sensitivitytoantibioticsofbacteriaexposedtogammaradiationemittedfromhotsoilsofthehighbackgroundradiationareasoframsarnortherniran AT samanehmasoomi sensitivitytoantibioticsofbacteriaexposedtogammaradiationemittedfromhotsoilsofthehighbackgroundradiationareasoframsarnortherniran AT leilaansari sensitivitytoantibioticsofbacteriaexposedtogammaradiationemittedfromhotsoilsofthehighbackgroundradiationareasoframsarnortherniran AT mohammadmehdimovahedi sensitivitytoantibioticsofbacteriaexposedtogammaradiationemittedfromhotsoilsofthehighbackgroundradiationareasoframsarnortherniran AT shahramtaeb sensitivitytoantibioticsofbacteriaexposedtogammaradiationemittedfromhotsoilsofthehighbackgroundradiationareasoframsarnortherniran AT sinazarei sensitivitytoantibioticsofbacteriaexposedtogammaradiationemittedfromhotsoilsofthehighbackgroundradiationareasoframsarnortherniran AT masoodhaghani sensitivitytoantibioticsofbacteriaexposedtogammaradiationemittedfromhotsoilsofthehighbackgroundradiationareasoframsarnortherniran |
_version_ |
1725081644993347584 |