Dosimetry of permanent interstitial prostate brachytherapy for an intraoperative procedure, using O-arm based CT and TRUS
Purpose: The aim of this report is dosimetric evaluation for an intraoperative fusion computed tomography (CT) as a superior predictor of 1-month CT based dosimetry in comparison to transrectal ultrasound (TRUS) in permanent interstitial prostate brachytherapy. Material and methods : Data of 65...
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2016-02-01
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doaj-cc8654b753a94dd3a87c1effe11c997d2020-11-24T22:33:38ZengTermedia Publishing HouseJournal of Contemporary Brachytherapy1689-832X2081-28412016-02-018171610.5114/jcb.2016.5781726936Dosimetry of permanent interstitial prostate brachytherapy for an intraoperative procedure, using O-arm based CT and TRUSHiromichi IshiyamaAkane SekiguchiTakefumi SatohHideyasu TsumuraKouji TakenakaShogo KawakamiKen-ichi TabataKentaro KobayashiMasatsugu IwamuraKazushige HayakawaPurpose: The aim of this report is dosimetric evaluation for an intraoperative fusion computed tomography (CT) as a superior predictor of 1-month CT based dosimetry in comparison to transrectal ultrasound (TRUS) in permanent interstitial prostate brachytherapy. Material and methods : Data of 65 patients treated with seed implantation were analyzed. All procedures has been performed with patients in the lithotomy position inside the O-arm system. An end-fine probe is used as a landmark to fuse TRUS and O-arm-based CT images. There was no difference in the patient’s position, probe position, and timing of image acquisition between the two imaging modalities. Dose-volume histogram (DVH) parameters such as the dose to 90% of prostate volume (D 90 ) has been analyzed. Results: The area under the curve of the receiver operating characteristic tended to be larger on fusion CT than on TRUS for most DVH parameters (71.85% vs. 59.59% for D 90 ; p = 0.07). Significant relationships between fusion CT and 1-month CT were confirmed using Pearson’s correlation coefficients for most DVH parameters (R = 0.48, p < 0.01 for D 90 ), although the relationship between TRUS and 1-month CT was poor. Large dose reduction (35 Gy for D 90 ) was seen from TRUS to fusion CT, especially in patients with high body weight and small prostate volume. Conclusions : Intraoperative fusion CT appears to have higher predictive power for 1-month CT-based dosimetry than TRUS. A prospective trial using fusion CT-based planning is warranted.https://www.termedia.pl/Dosimetry-of-permanent-interstitial-prostate-brachytherapy-for-an-intraoperative-procedure-using-O-arm-based-CT-and-TRUS,54,26936,1,1.htmlbrachytherapy intraoperative CT low dose rate O-arm system prostate cancer |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Hiromichi Ishiyama Akane Sekiguchi Takefumi Satoh Hideyasu Tsumura Kouji Takenaka Shogo Kawakami Ken-ichi Tabata Kentaro Kobayashi Masatsugu Iwamura Kazushige Hayakawa |
spellingShingle |
Hiromichi Ishiyama Akane Sekiguchi Takefumi Satoh Hideyasu Tsumura Kouji Takenaka Shogo Kawakami Ken-ichi Tabata Kentaro Kobayashi Masatsugu Iwamura Kazushige Hayakawa Dosimetry of permanent interstitial prostate brachytherapy for an intraoperative procedure, using O-arm based CT and TRUS Journal of Contemporary Brachytherapy brachytherapy intraoperative CT low dose rate O-arm system prostate cancer |
author_facet |
Hiromichi Ishiyama Akane Sekiguchi Takefumi Satoh Hideyasu Tsumura Kouji Takenaka Shogo Kawakami Ken-ichi Tabata Kentaro Kobayashi Masatsugu Iwamura Kazushige Hayakawa |
author_sort |
Hiromichi Ishiyama |
title |
Dosimetry of permanent interstitial prostate brachytherapy for an intraoperative procedure, using O-arm based CT and TRUS |
title_short |
Dosimetry of permanent interstitial prostate brachytherapy for an intraoperative procedure, using O-arm based CT and TRUS |
title_full |
Dosimetry of permanent interstitial prostate brachytherapy for an intraoperative procedure, using O-arm based CT and TRUS |
title_fullStr |
Dosimetry of permanent interstitial prostate brachytherapy for an intraoperative procedure, using O-arm based CT and TRUS |
title_full_unstemmed |
Dosimetry of permanent interstitial prostate brachytherapy for an intraoperative procedure, using O-arm based CT and TRUS |
title_sort |
dosimetry of permanent interstitial prostate brachytherapy for an intraoperative procedure, using o-arm based ct and trus |
publisher |
Termedia Publishing House |
series |
Journal of Contemporary Brachytherapy |
issn |
1689-832X 2081-2841 |
publishDate |
2016-02-01 |
description |
Purpose: The aim of this report is dosimetric evaluation for an intraoperative fusion computed tomography (CT) as a superior predictor of 1-month CT based dosimetry in comparison to transrectal ultrasound (TRUS) in permanent interstitial prostate brachytherapy.
Material and methods : Data of 65 patients treated with seed implantation were analyzed. All procedures has been performed with patients in the lithotomy position inside the O-arm system. An end-fine probe is used as a landmark to fuse TRUS and O-arm-based CT images. There was no difference in the patient’s position, probe position, and timing of image acquisition between the two imaging modalities. Dose-volume histogram (DVH) parameters such as the dose to 90% of prostate volume (D 90 ) has been analyzed.
Results: The area under the curve of the receiver operating characteristic tended to be larger on fusion CT than on TRUS for most DVH parameters (71.85% vs. 59.59% for D 90 ; p = 0.07). Significant relationships between fusion CT and 1-month CT were confirmed using Pearson’s correlation coefficients for most DVH parameters (R = 0.48, p < 0.01 for D 90 ), although the relationship between TRUS and 1-month CT was poor. Large dose reduction (35 Gy for D 90 ) was seen from TRUS to fusion CT, especially in patients with high body weight and small prostate volume.
Conclusions : Intraoperative fusion CT appears to have higher predictive power for 1-month CT-based dosimetry than TRUS. A prospective trial using fusion CT-based planning is warranted. |
topic |
brachytherapy intraoperative CT low dose rate O-arm system prostate cancer |
url |
https://www.termedia.pl/Dosimetry-of-permanent-interstitial-prostate-brachytherapy-for-an-intraoperative-procedure-using-O-arm-based-CT-and-TRUS,54,26936,1,1.html |
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