In-Stent Thrombosis after Antiplatelet Therapy Conversion while Awaiting Coronary Bypass

In-stent thrombosis (IST) is a rare yet dangerous complication that may occur despite optimized coronary intervention in the cardiac catheterization laboratory. This is a case of an 81-year-old man who presented with ST-elevation myocardial infarction. Right coronary artery (RCA) occlusion was suspe...

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Main Authors:	Nathan Burke, BS, Tawanna Charlton, MS, Hussam Hawamdeh, MD, Ki Park, MD, MS
Format:	Article
Language:	English
Published:	Compuscript 2020-11-01
Series:	Cardiovascular Innovations and Applications
Subjects:	acute myocardial infarction/st-elevation myocardial infarction antiplatelet therapy genetics platelet biology drug-eluting stent drugs/pharmacotherapy
Online Access:	https://www.ingentaconnect.com/content/cscript/cvia/2020/00000005/00000002/art00009

id	doaj-cc8f9267662b450fa529fac1dd394ef4
record_format	Article
spelling	doaj-cc8f9267662b450fa529fac1dd394ef42020-12-03T12:33:57ZengCompuscriptCardiovascular Innovations and Applications2009-86182009-87822020-11-015213914310.15212/CVIA.2019.0589In-Stent Thrombosis after Antiplatelet Therapy Conversion while Awaiting Coronary BypassNathan Burke, BS0Tawanna Charlton, MS1Hussam Hawamdeh, MD2Ki Park, MD, MS3Division of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, Florida, USADivision of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, Florida, USADivision of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, Florida, USADivision of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, Florida, USAIn-stent thrombosis (IST) is a rare yet dangerous complication that may occur despite optimized coronary intervention in the cardiac catheterization laboratory. This is a case of an 81-year-old man who presented with ST-elevation myocardial infarction. Right coronary artery (RCA) occlusion was suspected. RCA angiography and percutaneous coronary intervention were performed. Complicated left coronary artery disease was subsequently discovered. Per cardiothoracic surgeon request, the patient was transitioned from ticagrelor to clopidogrel therapy in preparation for coronary artery bypass grafting. The patient experienced IST the day before surgery while receiving clopidogrel. We examine this case, which highlights the complexity of antiplatelet therapy choice and the role of genetic testing in evaluation of IST risk.https://www.ingentaconnect.com/content/cscript/cvia/2020/00000005/00000002/art00009acute myocardial infarction/st-elevation myocardial infarctionantiplatelet therapygeneticsplatelet biologydrug-eluting stentdrugs/pharmacotherapy
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Nathan Burke, BS Tawanna Charlton, MS Hussam Hawamdeh, MD Ki Park, MD, MS
spellingShingle	Nathan Burke, BS Tawanna Charlton, MS Hussam Hawamdeh, MD Ki Park, MD, MS In-Stent Thrombosis after Antiplatelet Therapy Conversion while Awaiting Coronary Bypass Cardiovascular Innovations and Applications acute myocardial infarction/st-elevation myocardial infarction antiplatelet therapy genetics platelet biology drug-eluting stent drugs/pharmacotherapy
author_facet	Nathan Burke, BS Tawanna Charlton, MS Hussam Hawamdeh, MD Ki Park, MD, MS
author_sort	Nathan Burke, BS
title	In-Stent Thrombosis after Antiplatelet Therapy Conversion while Awaiting Coronary Bypass
title_short	In-Stent Thrombosis after Antiplatelet Therapy Conversion while Awaiting Coronary Bypass
title_full	In-Stent Thrombosis after Antiplatelet Therapy Conversion while Awaiting Coronary Bypass
title_fullStr	In-Stent Thrombosis after Antiplatelet Therapy Conversion while Awaiting Coronary Bypass
title_full_unstemmed	In-Stent Thrombosis after Antiplatelet Therapy Conversion while Awaiting Coronary Bypass
title_sort	in-stent thrombosis after antiplatelet therapy conversion while awaiting coronary bypass
publisher	Compuscript
series	Cardiovascular Innovations and Applications
issn	2009-8618 2009-8782
publishDate	2020-11-01
description	In-stent thrombosis (IST) is a rare yet dangerous complication that may occur despite optimized coronary intervention in the cardiac catheterization laboratory. This is a case of an 81-year-old man who presented with ST-elevation myocardial infarction. Right coronary artery (RCA) occlusion was suspected. RCA angiography and percutaneous coronary intervention were performed. Complicated left coronary artery disease was subsequently discovered. Per cardiothoracic surgeon request, the patient was transitioned from ticagrelor to clopidogrel therapy in preparation for coronary artery bypass grafting. The patient experienced IST the day before surgery while receiving clopidogrel. We examine this case, which highlights the complexity of antiplatelet therapy choice and the role of genetic testing in evaluation of IST risk.
topic	acute myocardial infarction/st-elevation myocardial infarction antiplatelet therapy genetics platelet biology drug-eluting stent drugs/pharmacotherapy
url	https://www.ingentaconnect.com/content/cscript/cvia/2020/00000005/00000002/art00009
work_keys_str_mv	AT nathanburkebs instentthrombosisafterantiplatelettherapyconversionwhileawaitingcoronarybypass AT tawannacharltonms instentthrombosisafterantiplatelettherapyconversionwhileawaitingcoronarybypass AT hussamhawamdehmd instentthrombosisafterantiplatelettherapyconversionwhileawaitingcoronarybypass AT kiparkmdms instentthrombosisafterantiplatelettherapyconversionwhileawaitingcoronarybypass
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In-Stent Thrombosis after Antiplatelet Therapy Conversion while Awaiting Coronary Bypass

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