Assessment of hepatitis C risk factors in center of Iran: A case–control study
Background: Hepatitis C virus (HCV) infections remain as one of the major public health problems worldwide. The current study aimed at investigating the potential risk factors of HCV+ in a sample of Iranian patients. Materials and Methods: In a case–control study, 436 HCV-infected patients and 531 a...
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doaj-cc9adf35f56b4b33be12c97017e0e3882020-11-25T00:23:15ZengWolters Kluwer Medknow PublicationsJournal of Research in Medical Sciences1735-19951735-71362018-01-01231878710.4103/jrms.JRMS_1211_17Assessment of hepatitis C risk factors in center of Iran: A case–control studyFaramarz Shahriari-FardSayed Moayed AlavianZiba FarajzadeganAli RabieiBehrooz AtaeiMehdi AtaieBackground: Hepatitis C virus (HCV) infections remain as one of the major public health problems worldwide. The current study aimed at investigating the potential risk factors of HCV+ in a sample of Iranian patients. Materials and Methods: In a case–control study, 436 HCV-infected patients and 531 age-matched HCV antibody negative controls were recruited in a central region of Iran. Sociodemographic characteristics, blood and therapeutic factors, underlying diseases, and behavioral risk factors were evaluated through a standard checklist and compared between two study groups. Results: Although among studied potential risk factors, many of them were significantly associated with infected with HCV; however, in multivariable logistic regression model in the presence of other variables being male gender (odds ratio [OR]: 4.1; 95% confidence interval [CI]: 2.2–7.8), illiterate or less educated (OR: 62.64; 95% CI: 5.94–660.35), having history of intravenous (IV) drug addiction (OR: 33.0; 95% CI: 5.43–250.0), and tattooing (OR: 14.29; 95% CI: 1.82–90.91) increased risk of infection with HCV. Conclusion: In total, the current case–control study documented that socioecomical factors including economical state, marital status, education, and ethnicity and also other expected factors such as hospitalization, imprisonment, dialysis, tattooing, needle sharing, IV drug abuse, and extramarital sexual relationship represent an important source of HCV infection among adults in a central region of Iran. Thus, we suggest further considerations for prevention of HCV infection as most of related factors are preventable by close considerations.http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2018;volume=23;issue=1;spage=87;epage=87;aulast=Shahriari-FardCase–control studieshepatitis CIranrisk factors |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Faramarz Shahriari-Fard Sayed Moayed Alavian Ziba Farajzadegan Ali Rabiei Behrooz Ataei Mehdi Ataie |
spellingShingle |
Faramarz Shahriari-Fard Sayed Moayed Alavian Ziba Farajzadegan Ali Rabiei Behrooz Ataei Mehdi Ataie Assessment of hepatitis C risk factors in center of Iran: A case–control study Journal of Research in Medical Sciences Case–control studies hepatitis C Iran risk factors |
author_facet |
Faramarz Shahriari-Fard Sayed Moayed Alavian Ziba Farajzadegan Ali Rabiei Behrooz Ataei Mehdi Ataie |
author_sort |
Faramarz Shahriari-Fard |
title |
Assessment of hepatitis C risk factors in center of Iran: A case–control study |
title_short |
Assessment of hepatitis C risk factors in center of Iran: A case–control study |
title_full |
Assessment of hepatitis C risk factors in center of Iran: A case–control study |
title_fullStr |
Assessment of hepatitis C risk factors in center of Iran: A case–control study |
title_full_unstemmed |
Assessment of hepatitis C risk factors in center of Iran: A case–control study |
title_sort |
assessment of hepatitis c risk factors in center of iran: a case–control study |
publisher |
Wolters Kluwer Medknow Publications |
series |
Journal of Research in Medical Sciences |
issn |
1735-1995 1735-7136 |
publishDate |
2018-01-01 |
description |
Background: Hepatitis C virus (HCV) infections remain as one of the major public health problems worldwide. The current study aimed at investigating the potential risk factors of HCV+ in a sample of Iranian patients. Materials and Methods: In a case–control study, 436 HCV-infected patients and 531 age-matched HCV antibody negative controls were recruited in a central region of Iran. Sociodemographic characteristics, blood and therapeutic factors, underlying diseases, and behavioral risk factors were evaluated through a standard checklist and compared between two study groups. Results: Although among studied potential risk factors, many of them were significantly associated with infected with HCV; however, in multivariable logistic regression model in the presence of other variables being male gender (odds ratio [OR]: 4.1; 95% confidence interval [CI]: 2.2–7.8), illiterate or less educated (OR: 62.64; 95% CI: 5.94–660.35), having history of intravenous (IV) drug addiction (OR: 33.0; 95% CI: 5.43–250.0), and tattooing (OR: 14.29; 95% CI: 1.82–90.91) increased risk of infection with HCV. Conclusion: In total, the current case–control study documented that socioecomical factors including economical state, marital status, education, and ethnicity and also other expected factors such as hospitalization, imprisonment, dialysis, tattooing, needle sharing, IV drug abuse, and extramarital sexual relationship represent an important source of HCV infection among adults in a central region of Iran. Thus, we suggest further considerations for prevention of HCV infection as most of related factors are preventable by close considerations. |
topic |
Case–control studies hepatitis C Iran risk factors |
url |
http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2018;volume=23;issue=1;spage=87;epage=87;aulast=Shahriari-Fard |
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