Insights into the Therapeutic Potential of Glucocorticoid Receptor Modulators for Neurodegenerative Diseases
Glucocorticoids are crucial for stress-coping, resilience, and adaptation. However, if the stress hormones become dysregulated, the vulnerability to stress-related diseases is enhanced. In this brief review, we discuss the role of glucocorticoids in the pathogenesis of neurodegenerative disorders in...
Main Authors: | Alejandro F. De Nicola, Maria Meyer, Rachida Guennoun, Michael Schumacher, Hazel Hunt, Joseph Belanoff, E. Ronald de Kloet, Maria Claudia Gonzalez Deniselle |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-03-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/21/6/2137 |
Similar Items
-
Progesterone Neuroprotection in the Wobbler Mouse, a Genetic Model of Spinal Cord Motor Neuron Disease
by: Marı́a Claudia Gonzalez Deniselle, et al.
Published: (2002-12-01) -
Intricate effects of primary motor neuronopathy on contractile proteins and metabolic muscle enzymes as revealed by label-free mass spectrometry
by: Ashling Holland, et al.
Published: (2014-07-01) -
Inflammation in Parkinson’s disease: Role of glucocorticoids
by: Maria Trinidad eHerrero, et al.
Published: (2015-04-01) -
Chitotriosidase, a biomarker of amyotrophic lateral sclerosis, accentuates neurodegeneration in spinal motor neurons through neuroinflammation
by: Anu Mary Varghese, et al.
Published: (2020-08-01) -
The Chitinases as Biomarkers for Amyotrophic Lateral Sclerosis: Signals From the CNS and Beyond
by: Nayana Gaur, et al.
Published: (2020-05-01)