Effect of fentanyl on diagnosis and treatment of painless gastroscopy

• Main Authors: Jing-Jing Du, Hong-Xia Zhu, Xin-Jing Su
• Format: Article
• Language: English
• Published: Editorial Board of Journal of Hainan Medical University 2016-12-01
• Series: Journal of Hainan Medical University
• Subjects: Painless gastroscopy; Fentanyl; Nasal administration; Adverse reaction
• Online Access: http://www.hnykdxxb.com/PDF/201624/43.pdf
• ISSN: 1007-1237; 1007-1237

Objective: To observe the effect of nasal and intravenous administrations of fentanyl in application of the diagnosis and treatment of painless gastroscopy. Methods: A total of 64 patients who were admitted in our hospital for painless gastroscopy were included in the study and randomized into the observation group and the control group with 32 cases in each group. The patients in the observation group were given nasal administration of fentanyl, while the patients in the control group were given intravenous administration of fentanyl. The dynamic changes of BP, HR, and SpO2 in the two groups were observed. A-line anesthesia depth monitor was used to monitor AAI. Propofol dosage, consultation time, bucking, and limb movement in the two groups were compared. Results: The fluctuation of BP, HR, and SpO2 during the diagnosis and treatment process in the observation group was less when compared with before treatment (P>0.05). BP was decreased, HR was slow down, and SpO2 was reduced during the diagnosis and treatment process in the control group when compared with before treatment and the observation group (P<0.05). AAI value 8 min after administration in the observation group was significantly lower than that in the control group (P<0.05). Thee occurrence rate of bucking and limb movement during the diagnosis and treatment process in the control group was significantly higher than that in the observation group (P<0.05). Conclusions: Nasal administration of fentanyl applied in the diagnosis and treatment of painless gastroscopy has a reliable clinical effect and small effect on the vital signs, and can significantly reduce the occurrence rate of adverse reactions.