Risk Factors for Death of Advanced Lung Cancer Patients with Lung Infection

• Main Authors: XIE Zhaoyun, QIN Jialu, XIONG Yun, LIU Liang, WEI Hua
• Format: Article
• Language: zho
• Published: Magazine House of Cancer Research on Prevention and Treatment 2018-04-01
• Series: Zhongliu Fangzhi Yanjiu
• Subjects: lung cancer; lung infection; death; risk factors; logistic regression analysis
• Online Access: http://html.rhhz.net/ZLFZYJ/html/8578.2018.17.0993.htm

Objective To analyze the risk factors of death in lung cancer patients with pulmonary infection. Methods From January 2010 to May 2017, 186 advanced lung cancer patients were treated, among which 52 patients with pulmonary infection died. Risk factors for the death of pulmonary infection were collected. Results The mortality rate of lung infection in advanced lung cancer patients was 27.96% (52/186). The differences of age (P=0.039), BMI value (P=0.000), low degree of differentiation (P=0.003), functional status score (P=0.022), ≥3 metastatic sites (P=0.029), complications (P=0.034), multiple resistant bacteria infection (P=0.000), hemoglobin concentration < 90g/L (P=0.014) between the death group and survival group were statistically significant. Conclusion Age (≥60 years old), BMI value (< 20kg/m2), histological grade (low), anti-tumour drugs treatment (≥3 regimens), targeted drug therapy, metastatic sites (≥3), complications, multiple resistant bacteria infection, hemoglobin concentration (< 90g/L) are the main risk factors for the death of advanced cancer patients with pulmonary infection.