Heparanase promotes neuroinflammatory response during subarachnoid hemorrhage in rats

Heparanase promotes neuroinflammatory response during subarachnoid hemorrhage in rats

Abstract Background Heparanase, a mammalian endo-β-D-glucoronidase that specifically degrades heparan sulfate, has been implicated in inflammation and ischemic stroke. However, the role of heparanase in neuroinflammatory response in subarachnoid hemorrhage (SAH) has not yet been investigated. This s...

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Bibliographic Details
Main Authors: Benjarat Changyaleket, Zhao Zhong Chong, Randal O. Dull, Danop Nanegrungsunk, Haoliang Xu
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Journal of Neuroinflammation
Subjects:
Heparanase
Inflammation
Subarachnoid hemorrhage
Neurological function
Online Access:http://link.springer.com/article/10.1186/s12974-017-0912-8

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