Effectiveness of using preservative-free artificial tears versus preserved lubricants for the treatment of dry eyes: a systematic review
ABSTRACT This systematic review aimed to assess the effectiveness of using preservative-free artificial tears versus preserved lubricants for the treatment of dry eyes in Universidade Federal de Alagoas (PROSPERO 2018 CRD42018089933). Online databases were searched (LILACS, EMBASE, MEDLINE, and CENT...
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doaj-ccdfbd69bd6742e58d1f27f2f72e57382020-11-24T21:27:48ZengConselho Brasileiro de OftalmologiaArquivos Brasileiros de Oftalmologia1678-292582543644510.5935/0004-2749.20190097S0004-27492019000500436Effectiveness of using preservative-free artificial tears versus preserved lubricants for the treatment of dry eyes: a systematic reviewMarina Viegas Moura Rezende RibeiroFabiano Timbó BarbosaLuiz Eduardo Feliciano RibeiroCélio Fernando de Sousa-RodriguesEurica Adélia Nogueira RibeiroABSTRACT This systematic review aimed to assess the effectiveness of using preservative-free artificial tears versus preserved lubricants for the treatment of dry eyes in Universidade Federal de Alagoas (PROSPERO 2018 CRD42018089933). Online databases were searched (LILACS, EMBASE, MEDLINE, and CENTRAL) from inception to April 2018; references from included papers were also searched. The following keywords were used: lubricants OR artificial tears OR artificial tears, lubricants AND dry eye OR dry eye syndrome OR syndromes, dry eye OR dry eyes. Among the 2028 electronic search results, 29 full papers were retrieved and four were considered relevant. The number of participants from these studies ranged from 15 to 76. Meta-analysis was possible for the following outcomes: score of symptoms according to the Ocular Surface Disease Index - Allergan (OSDI), tear secretion rate using the Schirmer test, tear evaporation rate using the tear film breakup time test, burning, foreign body sensation, and photophobia. No statistically significant difference was observed between the two groups, and no side effects were attributed to the interventions. Evidence proving that preservative-free artificial tears are more effective than preserved artificial tears is lacking.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492019000500436&lng=en&tlng=enDry eye syndromes/drug therapyLubricant eye drops/therapeutic useTearsSystematic review |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Marina Viegas Moura Rezende Ribeiro Fabiano Timbó Barbosa Luiz Eduardo Feliciano Ribeiro Célio Fernando de Sousa-Rodrigues Eurica Adélia Nogueira Ribeiro |
spellingShingle |
Marina Viegas Moura Rezende Ribeiro Fabiano Timbó Barbosa Luiz Eduardo Feliciano Ribeiro Célio Fernando de Sousa-Rodrigues Eurica Adélia Nogueira Ribeiro Effectiveness of using preservative-free artificial tears versus preserved lubricants for the treatment of dry eyes: a systematic review Arquivos Brasileiros de Oftalmologia Dry eye syndromes/drug therapy Lubricant eye drops/therapeutic use Tears Systematic review |
author_facet |
Marina Viegas Moura Rezende Ribeiro Fabiano Timbó Barbosa Luiz Eduardo Feliciano Ribeiro Célio Fernando de Sousa-Rodrigues Eurica Adélia Nogueira Ribeiro |
author_sort |
Marina Viegas Moura Rezende Ribeiro |
title |
Effectiveness of using preservative-free artificial tears versus preserved lubricants for the treatment of dry eyes: a systematic review |
title_short |
Effectiveness of using preservative-free artificial tears versus preserved lubricants for the treatment of dry eyes: a systematic review |
title_full |
Effectiveness of using preservative-free artificial tears versus preserved lubricants for the treatment of dry eyes: a systematic review |
title_fullStr |
Effectiveness of using preservative-free artificial tears versus preserved lubricants for the treatment of dry eyes: a systematic review |
title_full_unstemmed |
Effectiveness of using preservative-free artificial tears versus preserved lubricants for the treatment of dry eyes: a systematic review |
title_sort |
effectiveness of using preservative-free artificial tears versus preserved lubricants for the treatment of dry eyes: a systematic review |
publisher |
Conselho Brasileiro de Oftalmologia |
series |
Arquivos Brasileiros de Oftalmologia |
issn |
1678-2925 |
description |
ABSTRACT This systematic review aimed to assess the effectiveness of using preservative-free artificial tears versus preserved lubricants for the treatment of dry eyes in Universidade Federal de Alagoas (PROSPERO 2018 CRD42018089933). Online databases were searched (LILACS, EMBASE, MEDLINE, and CENTRAL) from inception to April 2018; references from included papers were also searched. The following keywords were used: lubricants OR artificial tears OR artificial tears, lubricants AND dry eye OR dry eye syndrome OR syndromes, dry eye OR dry eyes. Among the 2028 electronic search results, 29 full papers were retrieved and four were considered relevant. The number of participants from these studies ranged from 15 to 76. Meta-analysis was possible for the following outcomes: score of symptoms according to the Ocular Surface Disease Index - Allergan (OSDI), tear secretion rate using the Schirmer test, tear evaporation rate using the tear film breakup time test, burning, foreign body sensation, and photophobia. No statistically significant difference was observed between the two groups, and no side effects were attributed to the interventions. Evidence proving that preservative-free artificial tears are more effective than preserved artificial tears is lacking. |
topic |
Dry eye syndromes/drug therapy Lubricant eye drops/therapeutic use Tears Systematic review |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492019000500436&lng=en&tlng=en |
work_keys_str_mv |
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