496 Immune cell profiling across solid tumor types by mass cytometry reveals tumor enrichment of PD-1+/LAG-3+ CD8 memory T cells that exhibit tumor-reactive yet dysfunctional features
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMJ Publishing Group
2020-11-01
|
| Series: | Journal for ImmunoTherapy of Cancer |
| id |
doaj-cd2b322619b846c38bc2770016928ae2 |
|---|---|
| record_format |
Article |
| spelling |
doaj-cd2b322619b846c38bc2770016928ae22020-12-11T10:02:23ZengBMJ Publishing GroupJournal for ImmunoTherapy of Cancer2051-14262020-11-018Suppl 310.1136/jitc-2020-SITC2020.0496496 Immune cell profiling across solid tumor types by mass cytometry reveals tumor enrichment of PD-1+/LAG-3+ CD8 memory T cells that exhibit tumor-reactive yet dysfunctional featuresJustin David0Miye Jacques1Bradley Garman2Laurence Menard3Can Jiang4Sherif Daouti5Priyanka Mehta6Mohan Bolisetty7Nataly Manjarrez Orduno8Aff1 Laboratory of Tumor Immunology and Biology CCR, NCI, NIH USA SQZ Biotechnologies, Watertown, MA, USABristol Myers Squibb, Lawrenceville, NJ, USABristol Myers Squibb, Lawrenceville, NJ, USABristol Myers Squibb, Lawrenceville, NJ, USABristol Myers Squibb, Lawrenceville, NJ, USABristol Myers Squibb, Lawrenceville, NJ, USABristol Myers Squibb, Lawrenceville, NJ, USABristol Myers Squibb, Lawrenceville, NJ, USA |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Justin David Miye Jacques Bradley Garman Laurence Menard Can Jiang Sherif Daouti Priyanka Mehta Mohan Bolisetty Nataly Manjarrez Orduno |
| spellingShingle |
Justin David Miye Jacques Bradley Garman Laurence Menard Can Jiang Sherif Daouti Priyanka Mehta Mohan Bolisetty Nataly Manjarrez Orduno 496 Immune cell profiling across solid tumor types by mass cytometry reveals tumor enrichment of PD-1+/LAG-3+ CD8 memory T cells that exhibit tumor-reactive yet dysfunctional features Journal for ImmunoTherapy of Cancer |
| author_facet |
Justin David Miye Jacques Bradley Garman Laurence Menard Can Jiang Sherif Daouti Priyanka Mehta Mohan Bolisetty Nataly Manjarrez Orduno |
| author_sort |
Justin David |
| title |
496 Immune cell profiling across solid tumor types by mass cytometry reveals tumor enrichment of PD-1+/LAG-3+ CD8 memory T cells that exhibit tumor-reactive yet dysfunctional features |
| title_short |
496 Immune cell profiling across solid tumor types by mass cytometry reveals tumor enrichment of PD-1+/LAG-3+ CD8 memory T cells that exhibit tumor-reactive yet dysfunctional features |
| title_full |
496 Immune cell profiling across solid tumor types by mass cytometry reveals tumor enrichment of PD-1+/LAG-3+ CD8 memory T cells that exhibit tumor-reactive yet dysfunctional features |
| title_fullStr |
496 Immune cell profiling across solid tumor types by mass cytometry reveals tumor enrichment of PD-1+/LAG-3+ CD8 memory T cells that exhibit tumor-reactive yet dysfunctional features |
| title_full_unstemmed |
496 Immune cell profiling across solid tumor types by mass cytometry reveals tumor enrichment of PD-1+/LAG-3+ CD8 memory T cells that exhibit tumor-reactive yet dysfunctional features |
| title_sort |
496 immune cell profiling across solid tumor types by mass cytometry reveals tumor enrichment of pd-1+/lag-3+ cd8 memory t cells that exhibit tumor-reactive yet dysfunctional features |
| publisher |
BMJ Publishing Group |
| series |
Journal for ImmunoTherapy of Cancer |
| issn |
2051-1426 |
| publishDate |
2020-11-01 |
| work_keys_str_mv |
AT justindavid 496immunecellprofilingacrosssolidtumortypesbymasscytometryrevealstumorenrichmentofpd1lag3cd8memorytcellsthatexhibittumorreactiveyetdysfunctionalfeatures AT miyejacques 496immunecellprofilingacrosssolidtumortypesbymasscytometryrevealstumorenrichmentofpd1lag3cd8memorytcellsthatexhibittumorreactiveyetdysfunctionalfeatures AT bradleygarman 496immunecellprofilingacrosssolidtumortypesbymasscytometryrevealstumorenrichmentofpd1lag3cd8memorytcellsthatexhibittumorreactiveyetdysfunctionalfeatures AT laurencemenard 496immunecellprofilingacrosssolidtumortypesbymasscytometryrevealstumorenrichmentofpd1lag3cd8memorytcellsthatexhibittumorreactiveyetdysfunctionalfeatures AT canjiang 496immunecellprofilingacrosssolidtumortypesbymasscytometryrevealstumorenrichmentofpd1lag3cd8memorytcellsthatexhibittumorreactiveyetdysfunctionalfeatures AT sherifdaouti 496immunecellprofilingacrosssolidtumortypesbymasscytometryrevealstumorenrichmentofpd1lag3cd8memorytcellsthatexhibittumorreactiveyetdysfunctionalfeatures AT priyankamehta 496immunecellprofilingacrosssolidtumortypesbymasscytometryrevealstumorenrichmentofpd1lag3cd8memorytcellsthatexhibittumorreactiveyetdysfunctionalfeatures AT mohanbolisetty 496immunecellprofilingacrosssolidtumortypesbymasscytometryrevealstumorenrichmentofpd1lag3cd8memorytcellsthatexhibittumorreactiveyetdysfunctionalfeatures AT natalymanjarrezorduno 496immunecellprofilingacrosssolidtumortypesbymasscytometryrevealstumorenrichmentofpd1lag3cd8memorytcellsthatexhibittumorreactiveyetdysfunctionalfeatures |
| _version_ |
1724386608595075072 |