Interventricular mechanical dyssynchrony in dilated cardiomyopathy and its relation with left ventricular systolic dysfunction

• Main Authors: Ahlam Kadhim Abbood, Haider Jabar Al-Ghizzi, Wissam S Tajuldin
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2018-01-01
• Series: Medical Journal of Babylon
• Subjects: Dilated cardiomyopathy; dyssynchrony; systolic dysfunction
• Online Access: http://www.medjbabylon.org/article.asp?issn=1812-156X;year=2018;volume=15;issue=3;spage=227;epage=230;aulast=Abbood
• ISSN: 1812-156X; 2312-6760

Background: Heart failure (HF) is a major problem worldwide, and despite the optimal medical treatment, still it carries high mortality. Ventricular dyssynchrony among patient with HF portends poor prognosis. Aim of the Study: The aim is to evaluate the prevalence of interventricular dyssynchrony in patients with dilated cardiomyopathy (DCM) patients and its relation to underlying etiology and the severity of systolic dysfunction. Materials and Methods: Fifty-eight patients with ischemic and nonischemic cardiomyopathy (ICM and NCM) were included in this study. Inclusion criteria include Type II–IV New York Heart Association patients with ejection fraction (EF) <35%. Mechanical dyssynchrony (interventricular dyssynchrony) was assessed by pulsed Doppler. Assessment of left ventricular (LV) systolic function was by EF and stroke volume. Evaluation of the prevalence of mechanical indices in DCM and their relation to underlying etiology and severity of LV systolic dysfunction was done. Results: The prevalence of interventricular dyssynchrony was more in NCM than ICM. There was a nonsignificant negative correlation between this dyssynchrony and LV systolic parameters. Conclusion: Mechanical dyssynchrony indices were affected by the underlying etiology and severity of LV systolic dysfunction associated with the existence of the mechanical dyssynchrony.