Vacuolating cytotoxin A (VacA), a key toxin for Helicobacter pylori pathogenesis.

More than fifty percent of the world’s population is infected with Helicobacter pylori. Chronic infection with the Gram-negative pathogen is associated with the development of peptic ulcers and is linked to an increased risk of gastric cancer. H. pylori secrete many proteinaceous factors that are im...

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Bibliographic Details
Main Authors: Samuel Leslie Palframan, Terry eKwok, Kipros eGabriel
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2012.00092/full