Antimicrobial peptides in asthma pathogenesis
Antimicrobial peptides exhibit activity against bacteria, viruses, fungi, and parasites. They have been described not only as endogenous antibiotics but also as immune modulators with an impact on innate and adaptive immune functions. Asthma is one of the most common diseases, characterized by chron...
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doaj-cd8eefab316e4f72a9cd7eca83b8ff382020-11-25T00:34:23ZengIndex Copernicus International S.A.Postępy Higieny i Medycyny Doświadczalnej0032-54491732-26932015-01-0169101310.5604/01.3001.0009.647401.3001.0009.6474Antimicrobial peptides in asthma pathogenesisKrzysztof Pałgan0Marta Tykwińska1Zbigniew Bartuzi2Katedra i Klinika Alergologii, Immunologii Klinicznej i Chorób Wewnętrznych, Collegium Medicum w Bydgoszczy, UMK ToruńKatedra i Klinika Alergologii, Immunologii Klinicznej i Chorób Wewnętrznych, Collegium Medicum w Bydgoszczy, UMK ToruńKatedra i Klinika Alergologii, Immunologii Klinicznej i Chorób Wewnętrznych, Collegium Medicum w Bydgoszczy, UMK ToruńAntimicrobial peptides exhibit activity against bacteria, viruses, fungi, and parasites. They have been described not only as endogenous antibiotics but also as immune modulators with an impact on innate and adaptive immune functions. Asthma is one of the most common diseases, characterized by chronic airway inflammation, bronchial hyperreactivity and asthma attacks. Airway inflammation in asthma is characterized by allergic phenotypes, such as dense infiltration of eosinophils, mast cells, Th 2 lymphocytes and monocytes. Viral infections are often the cause of asthma exacerbation. This review highlights recent observations on the role of antimicrobial peptides in asthma pathogenesis. http://phmd.pl/gicid/01.3001.0009.6474antimicrobial peptidesDefensinscathelicidinAsthmavitamin D3 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Krzysztof Pałgan Marta Tykwińska Zbigniew Bartuzi |
spellingShingle |
Krzysztof Pałgan Marta Tykwińska Zbigniew Bartuzi Antimicrobial peptides in asthma pathogenesis Postępy Higieny i Medycyny Doświadczalnej antimicrobial peptides Defensins cathelicidin Asthma vitamin D3 |
author_facet |
Krzysztof Pałgan Marta Tykwińska Zbigniew Bartuzi |
author_sort |
Krzysztof Pałgan |
title |
Antimicrobial peptides in asthma pathogenesis |
title_short |
Antimicrobial peptides in asthma pathogenesis |
title_full |
Antimicrobial peptides in asthma pathogenesis |
title_fullStr |
Antimicrobial peptides in asthma pathogenesis |
title_full_unstemmed |
Antimicrobial peptides in asthma pathogenesis |
title_sort |
antimicrobial peptides in asthma pathogenesis |
publisher |
Index Copernicus International S.A. |
series |
Postępy Higieny i Medycyny Doświadczalnej |
issn |
0032-5449 1732-2693 |
publishDate |
2015-01-01 |
description |
Antimicrobial peptides exhibit activity against bacteria, viruses, fungi, and parasites. They have been described not only as endogenous antibiotics but also as immune modulators with an impact on innate and adaptive immune functions. Asthma is one of the most common diseases, characterized by chronic airway inflammation, bronchial hyperreactivity and asthma attacks. Airway inflammation in asthma is characterized by allergic phenotypes, such as dense infiltration of eosinophils, mast cells, Th 2 lymphocytes and monocytes. Viral infections are often the cause of asthma exacerbation. This review highlights recent observations on the role of antimicrobial peptides in asthma pathogenesis.
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topic |
antimicrobial peptides Defensins cathelicidin Asthma vitamin D3 |
url |
http://phmd.pl/gicid/01.3001.0009.6474 |
work_keys_str_mv |
AT krzysztofpałgan antimicrobialpeptidesinasthmapathogenesis AT martatykwinska antimicrobialpeptidesinasthmapathogenesis AT zbigniewbartuzi antimicrobialpeptidesinasthmapathogenesis |
_version_ |
1725313688697569280 |