Epidemic Profile of Maternal Syphilis in China in 2013
Objective. The aim of this study was to investigate the epidemiological characteristics and adverse pregnancy outcomes of pregnant women with syphilis infection in China. Methods. Data were from China’s Information System of Prevention of Mother-to-Child Transmission of Syphilis Management. Women wh...
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Series: | BioMed Research International |
Online Access: | http://dx.doi.org/10.1155/2016/9194805 |
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doaj-cd91364472494935822de20fbf7eb3872020-11-24T23:05:09ZengHindawi LimitedBioMed Research International2314-61332314-61412016-01-01201610.1155/2016/91948059194805Epidemic Profile of Maternal Syphilis in China in 2013Lixia Dou0Xiaoyan Wang1Fang Wang2Qian Wang3Yaping Qiao4Min Su5Xi Jin6Jie Qiu7Li Song8Ailing Wang9National Center for Women and Children’s Health, China CDC, No. 12 Dahuisi Road, Haidian District, Beijing 100081, ChinaNational Center for Women and Children’s Health, China CDC, No. 12 Dahuisi Road, Haidian District, Beijing 100081, ChinaNational Center for Women and Children’s Health, China CDC, No. 12 Dahuisi Road, Haidian District, Beijing 100081, ChinaNational Center for Women and Children’s Health, China CDC, No. 12 Dahuisi Road, Haidian District, Beijing 100081, ChinaNational Center for Women and Children’s Health, China CDC, No. 12 Dahuisi Road, Haidian District, Beijing 100081, ChinaNational Center for Women and Children’s Health, China CDC, No. 12 Dahuisi Road, Haidian District, Beijing 100081, ChinaNational Center for Women and Children’s Health, China CDC, No. 12 Dahuisi Road, Haidian District, Beijing 100081, ChinaNational Health and Family Planning Commission, No. 14 Zhichun Road, Haidian District, Beijing 100088, ChinaNational Health and Family Planning Commission, No. 14 Zhichun Road, Haidian District, Beijing 100088, ChinaNational Center for Women and Children’s Health, China CDC, No. 12 Dahuisi Road, Haidian District, Beijing 100081, ChinaObjective. The aim of this study was to investigate the epidemiological characteristics and adverse pregnancy outcomes of pregnant women with syphilis infection in China. Methods. Data were from China’s Information System of Prevention of Mother-to-Child Transmission of Syphilis Management. Women who were registered in the system and delivered in 2013 were included in the analysis. Results. A total of 15884 pregnant women with syphilis infection delivered in China in 2013. 79.1% of infected women attended antenatal care at or before 37 gestational weeks; however, 55.4% received no treatment or initiated the treatment after 37 gestational weeks. 14.0% of women suffered serious adverse pregnancy outcomes including stillbirth/neonatal death, preterm delivery/low birth weight, or congenital syphilis in newborns. High maternal titer (≥1 : 64) and late treatment (>37 gestational weeks)/nontreatment were significantly associated with increased risk of congenital syphilis and the adjusted ORs were 1.88 (95% CI 1.27 to 2.80) and 3.70 (95% CI 2.36 to 5.80), respectively. Conclusion. Syphilis affects a great number of pregnant women in China. Large proportions of women are not detected and treated at an early pregnancy stage. Burden of adverse pregnancy outcomes is high among infected women. Comprehensive interventions still need to be strengthened to improve uptake of screening and treatment for maternal syphilis.http://dx.doi.org/10.1155/2016/9194805 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Lixia Dou Xiaoyan Wang Fang Wang Qian Wang Yaping Qiao Min Su Xi Jin Jie Qiu Li Song Ailing Wang |
spellingShingle |
Lixia Dou Xiaoyan Wang Fang Wang Qian Wang Yaping Qiao Min Su Xi Jin Jie Qiu Li Song Ailing Wang Epidemic Profile of Maternal Syphilis in China in 2013 BioMed Research International |
author_facet |
Lixia Dou Xiaoyan Wang Fang Wang Qian Wang Yaping Qiao Min Su Xi Jin Jie Qiu Li Song Ailing Wang |
author_sort |
Lixia Dou |
title |
Epidemic Profile of Maternal Syphilis in China in 2013 |
title_short |
Epidemic Profile of Maternal Syphilis in China in 2013 |
title_full |
Epidemic Profile of Maternal Syphilis in China in 2013 |
title_fullStr |
Epidemic Profile of Maternal Syphilis in China in 2013 |
title_full_unstemmed |
Epidemic Profile of Maternal Syphilis in China in 2013 |
title_sort |
epidemic profile of maternal syphilis in china in 2013 |
publisher |
Hindawi Limited |
series |
BioMed Research International |
issn |
2314-6133 2314-6141 |
publishDate |
2016-01-01 |
description |
Objective. The aim of this study was to investigate the epidemiological characteristics and adverse pregnancy outcomes of pregnant women with syphilis infection in China. Methods. Data were from China’s Information System of Prevention of Mother-to-Child Transmission of Syphilis Management. Women who were registered in the system and delivered in 2013 were included in the analysis. Results. A total of 15884 pregnant women with syphilis infection delivered in China in 2013. 79.1% of infected women attended antenatal care at or before 37 gestational weeks; however, 55.4% received no treatment or initiated the treatment after 37 gestational weeks. 14.0% of women suffered serious adverse pregnancy outcomes including stillbirth/neonatal death, preterm delivery/low birth weight, or congenital syphilis in newborns. High maternal titer (≥1 : 64) and late treatment (>37 gestational weeks)/nontreatment were significantly associated with increased risk of congenital syphilis and the adjusted ORs were 1.88 (95% CI 1.27 to 2.80) and 3.70 (95% CI 2.36 to 5.80), respectively. Conclusion. Syphilis affects a great number of pregnant women in China. Large proportions of women are not detected and treated at an early pregnancy stage. Burden of adverse pregnancy outcomes is high among infected women. Comprehensive interventions still need to be strengthened to improve uptake of screening and treatment for maternal syphilis. |
url |
http://dx.doi.org/10.1155/2016/9194805 |
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