EFFECTS OF VOLUNTARY WHEEL RUNNING ON SATELLITE CELLS IN THE RAT PLANTARIS MUSCLE
This study investigated the effects of voluntary wheel running on satellite cells in the rat plantaris muscle. Seventeen 5-week-old male Wistar rats were assigned to a control (n = 5) or training (n = 12) group. Each rat in the training group ran voluntarily in a running-wheel cage for 8 weeks. Afte...
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University of Uludag
2009-03-01
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doaj-cd961548f3404db5b37d949a118787aa2020-11-24T22:21:24ZengUniversity of UludagJournal of Sports Science and Medicine1303-29682009-03-01815157EFFECTS OF VOLUNTARY WHEEL RUNNING ON SATELLITE CELLS IN THE RAT PLANTARIS MUSCLE Atsushi KojimaMitsutoshi KurosakaYuji OguraHisashi NaitoShizuo KatamotoKatsumasa GotoThis study investigated the effects of voluntary wheel running on satellite cells in the rat plantaris muscle. Seventeen 5-week-old male Wistar rats were assigned to a control (n = 5) or training (n = 12) group. Each rat in the training group ran voluntarily in a running-wheel cage for 8 weeks. After the training period, the animals were anesthetized, and the plantaris muscles were removed, weighed, and analyzed immunohistochemically and biochemically. Although there were no significant differences in muscle weight or fiber area between the groups, the numbers of satellite cells and myonuclei per muscle fiber, percentage of satellite cells, and citrate synthase activity were significantly higher in the training group compared with the control group (p < 0.05). The percentage of satellite cells was also positively correlated with distance run in the training group (r = 0.61, p < 0.05). Voluntary running can induce an increase in the number of satellite cells without changing the mean fiber area in the rat plantaris muscle; this increase in satellite cell content is a function of distance runhttp://www.jssm.org/vol8/n1/8/v8n1-8text.phpEndurance trainingmuscle damagehypertrophymyonuclearPax7 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Atsushi Kojima Mitsutoshi Kurosaka Yuji Ogura Hisashi Naito Shizuo Katamoto Katsumasa Goto |
spellingShingle |
Atsushi Kojima Mitsutoshi Kurosaka Yuji Ogura Hisashi Naito Shizuo Katamoto Katsumasa Goto EFFECTS OF VOLUNTARY WHEEL RUNNING ON SATELLITE CELLS IN THE RAT PLANTARIS MUSCLE Journal of Sports Science and Medicine Endurance training muscle damage hypertrophy myonuclear Pax7 |
author_facet |
Atsushi Kojima Mitsutoshi Kurosaka Yuji Ogura Hisashi Naito Shizuo Katamoto Katsumasa Goto |
author_sort |
Atsushi Kojima |
title |
EFFECTS OF VOLUNTARY WHEEL RUNNING ON SATELLITE CELLS IN THE RAT PLANTARIS MUSCLE |
title_short |
EFFECTS OF VOLUNTARY WHEEL RUNNING ON SATELLITE CELLS IN THE RAT PLANTARIS MUSCLE |
title_full |
EFFECTS OF VOLUNTARY WHEEL RUNNING ON SATELLITE CELLS IN THE RAT PLANTARIS MUSCLE |
title_fullStr |
EFFECTS OF VOLUNTARY WHEEL RUNNING ON SATELLITE CELLS IN THE RAT PLANTARIS MUSCLE |
title_full_unstemmed |
EFFECTS OF VOLUNTARY WHEEL RUNNING ON SATELLITE CELLS IN THE RAT PLANTARIS MUSCLE |
title_sort |
effects of voluntary wheel running on satellite cells in the rat plantaris muscle |
publisher |
University of Uludag |
series |
Journal of Sports Science and Medicine |
issn |
1303-2968 |
publishDate |
2009-03-01 |
description |
This study investigated the effects of voluntary wheel running on satellite cells in the rat plantaris muscle. Seventeen 5-week-old male Wistar rats were assigned to a control (n = 5) or training (n = 12) group. Each rat in the training group ran voluntarily in a running-wheel cage for 8 weeks. After the training period, the animals were anesthetized, and the plantaris muscles were removed, weighed, and analyzed immunohistochemically and biochemically. Although there were no significant differences in muscle weight or fiber area between the groups, the numbers of satellite cells and myonuclei per muscle fiber, percentage of satellite cells, and citrate synthase activity were significantly higher in the training group compared with the control group (p < 0.05). The percentage of satellite cells was also positively correlated with distance run in the training group (r = 0.61, p < 0.05). Voluntary running can induce an increase in the number of satellite cells without changing the mean fiber area in the rat plantaris muscle; this increase in satellite cell content is a function of distance run |
topic |
Endurance training muscle damage hypertrophy myonuclear Pax7 |
url |
http://www.jssm.org/vol8/n1/8/v8n1-8text.php |
work_keys_str_mv |
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