RNA-guided transcriptional activation via CRISPR/dCas9 mimics overexpression phenotypes in Arabidopsis.
Clustered regularly interspaced short palindromic repeats (CRISPR) and the CRISPR associated protein 9 (Cas9) system allows effective gene modification through RNA-guided DNA targeting. The Cas9 has undergone a series of functional alterations from the original active endonuclease to partially or co...
Main Authors: | Jong-Jin Park, Emma Dempewolf, Wenzheng Zhang, Zeng-Yu Wang |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5473554?pdf=render |
Similar Items
-
Versatile in vivo regulation of tumor phenotypes by dCas9-mediated transcriptional perturbation
by: Horlbeck, Max A., et al.
Published: (2018) -
RNA-guided Transcriptional Regulation in Plants via dCas9 Chimeric Proteins
by: Baazim, Hatoon
Published: (2014) -
Digital logic circuits in yeast with CRISPR-dCas9 NOR gates
by: Miles W. Gander, et al.
Published: (2017-05-01) -
A CRISPR/dCas9 toolkit for functional analysis of maize genes
by: Irene N. Gentzel, et al.
Published: (2020-10-01) -
Activating PTEN Tumor Suppressor Expression with the CRISPR/dCas9 System
by: Colette Moses, et al.
Published: (2019-03-01)