An Ideal PPAR Response Element Bound to and Activated by PPARα.

Peroxisome proliferator-activated receptor-α (PPARα), a nuclear receptor, plays an important role in the transcription of genes involved in fatty acid metabolism through heterodimerization with the retinoid x receptor (RXR). The consensus sequence of the PPAR response element (PPRE) is composed of t...

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Bibliographic Details
Main Authors: John Tzeng, Jaemin Byun, Ji Yeon Park, Takanobu Yamamoto, Kevin Schesing, Bin Tian, Junichi Sadoshima, Shin-Ichi Oka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4524655?pdf=render

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