Immune Dysregulation and the Increased Risk of Complications and Mortality Following Respiratory Tract Infections in Adults With Down Syndrome

Immune Dysregulation and the Increased Risk of Complications and Mortality Following Respiratory Tract Infections in Adults With Down Syndrome

The risk of severe outcomes following respiratory tract infections is significantly increased in individuals over 60 years, especially in those with chronic medical conditions, i.e., hypertension, diabetes, cardiovascular disease, dementia, chronic respiratory disease, and cancer. Down Syndrome (DS)...

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Bibliographic Details
Main Authors: Tomer Illouz, Arya Biragyn, Maria Florencia Iulita, Lisi Flores-Aguilar, Mara Dierssen, Ilario De Toma, Stylianos E. Antonarakis, Eugene Yu, Yann Herault, Marie-Claude Potier, Alexandra Botté, Randall Roper, Benjamin Sredni, Jacqueline London, William Mobley, Andre Strydom, Eitan Okun
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
Down syndrome
immune dysregulation
hospitalization
respiratory tract infections
interferon
COVID-19
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.621440/full

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