Lack of quadruple and quintuple mutant alleles associated with sulfadoxine-pyrimethamine resistance in Plasmodium vivax isolates from Brazilian endemic areas

BACKGROUND AND OBJECTIVE Brazil is responsible for a large number of Plasmodium vivax cases in America. Given the emergence of P. vivax parasites resistant to chloroquine and the effectiveness of antifolates in vivax malaria treatment together with a correlation between mutations in P. vivax dhfr a...

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Bibliographic Details
Main Authors: Larissa Rodrigues Gomes, Aline Lavigne, Patrícia Brasil, Cassio Leonel Peterka, Didier Ménard, Cláudio Tadeu Daniel-Ribeiro, Maria de Fátima Ferreira-da-Cruz
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2019-02-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762019000100309&lng=en&tlng=en