Phospholipid-Gold Nanorods Induce Energy Crisis in MCF-7 Cells: Cytotoxicity Evaluation Using LC-MS-Based Metabolomics Approach

Phospholipid-Gold Nanorods Induce Energy Crisis in MCF-7 Cells: Cytotoxicity Evaluation Using LC-MS-Based Metabolomics Approach

Phospholipid-modified gold nanorods (phospholipid-GNRs) have demonstrated drastic cytotoxicity towards MCF-7 breast cancer cells compared to polyethylene glycol-coated GNRs (PEG-GNRs). In this study, the mechanism of cytotoxicity of phospholipid-GNRs towards MCF-7 cells was investigated using mass s...

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Bibliographic Details
Main Authors: Lina A. Dahabiyeh, Nouf N. Mahmoud, Mohammad A. Al-Natour, Laudina Safo, Dong-Hyun Kim, Enam A. Khalil, Rana Abu-Dahab
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Biomolecules
Subjects:
gold nanorods
metabolomics
LC-MS
MCF-7
amino acids
energy metabolism
Online Access:https://www.mdpi.com/2218-273X/11/3/364

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