A Facile One-pot Synthesis of 1-Arylpyrazolo[3,4-d]Pyrimidin- 4-ones
One pot synthesis of 1-arylpyrazolo[3,4-d]pyrimidin-4-ones by the reaction of 5-amino-N-substituted-1H-pyrazole-4-carbonitrile with different lower aliphatic acids in the presence of POCl3has been developed. The structures of all the title compounds have been confirmed by IR, 1H-NMR, 13C-NMR, and el...
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| Format: | Article |
| Language: | English |
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MDPI AG
2010-04-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/15/5/3079/ |
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doaj-cdd1bf95d1dd445eaef0ff9802adc3042020-11-24T20:56:57ZengMDPI AGMolecules1420-30492010-04-011553079308610.3390/molecules15053079A Facile One-pot Synthesis of 1-Arylpyrazolo[3,4-d]Pyrimidin- 4-onesPing ZhongXiaohong ZhangQiulian LinOne pot synthesis of 1-arylpyrazolo[3,4-d]pyrimidin-4-ones by the reaction of 5-amino-N-substituted-1H-pyrazole-4-carbonitrile with different lower aliphatic acids in the presence of POCl3has been developed. The structures of all the title compounds have been confirmed by IR, 1H-NMR, 13C-NMR, and elemental analyses. Moreover, the structures of one of these compounds, 2c, was confirmed by single-crystal X-ray diffraction. http://www.mdpi.com/1420-3049/15/5/3079/POCl3one-potRCOOHpyrazolo[3,4-d]pyrimidine |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Ping Zhong Xiaohong Zhang Qiulian Lin |
| spellingShingle |
Ping Zhong Xiaohong Zhang Qiulian Lin A Facile One-pot Synthesis of 1-Arylpyrazolo[3,4-d]Pyrimidin- 4-ones Molecules POCl3 one-pot RCOOH pyrazolo[3,4-d]pyrimidine |
| author_facet |
Ping Zhong Xiaohong Zhang Qiulian Lin |
| author_sort |
Ping Zhong |
| title |
A Facile One-pot Synthesis of 1-Arylpyrazolo[3,4-d]Pyrimidin- 4-ones |
| title_short |
A Facile One-pot Synthesis of 1-Arylpyrazolo[3,4-d]Pyrimidin- 4-ones |
| title_full |
A Facile One-pot Synthesis of 1-Arylpyrazolo[3,4-d]Pyrimidin- 4-ones |
| title_fullStr |
A Facile One-pot Synthesis of 1-Arylpyrazolo[3,4-d]Pyrimidin- 4-ones |
| title_full_unstemmed |
A Facile One-pot Synthesis of 1-Arylpyrazolo[3,4-d]Pyrimidin- 4-ones |
| title_sort |
facile one-pot synthesis of 1-arylpyrazolo[3,4-d]pyrimidin- 4-ones |
| publisher |
MDPI AG |
| series |
Molecules |
| issn |
1420-3049 |
| publishDate |
2010-04-01 |
| description |
One pot synthesis of 1-arylpyrazolo[3,4-d]pyrimidin-4-ones by the reaction of 5-amino-N-substituted-1H-pyrazole-4-carbonitrile with different lower aliphatic acids in the presence of POCl3has been developed. The structures of all the title compounds have been confirmed by IR, 1H-NMR, 13C-NMR, and elemental analyses. Moreover, the structures of one of these compounds, 2c, was confirmed by single-crystal X-ray diffraction. |
| topic |
POCl3 one-pot RCOOH pyrazolo[3,4-d]pyrimidine |
| url |
http://www.mdpi.com/1420-3049/15/5/3079/ |
| work_keys_str_mv |
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