Protective effect of melatonin on blood⁃brain barrier dysfunction in rats with chronic cerebral hypoperfusion

Protective effect of melatonin on blood⁃brain barrier dysfunction in rats with chronic cerebral hypoperfusion

Objective To investigate the mechanism of the effect of melatonin (MT) on permeability of blood-brainbarrier (BBB) in chronic cerebral hypoperfusion (CCH) rats. Methods Therat model of CCH was established by bilateral common carotid artery occlusion (BCCAO). A total of 72 male Sprague-Dawley rats...

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Bibliographic Details
Main Authors:	Shao⁃peng WANG, Ru WANG, Dan⁃dan LI, Hong⁃yi ZHAO, Li⁃yi CHI, Yong⁃hua HUANG
Format:	Article
Language:	English
Published:	Tianjin Huanhu Hospital 2019-08-01
Series:	Chinese Journal of Contemporary Neurology and Neurosurgery
Subjects:	Cerebral small vessel diseases; Melatonin; Blood⁃brain barrier; Disease models animal
Online Access:	http://www.cjcnn.org/index.php/cjcnn/article/view/1993

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