Aloe vera as vehicle to mineral trioxide aggregate: study in bone repair
AIM: Mineral trioxide aggregate (MTA) was associated to Aloe vera to verify the coadjutant action of that medicinal plant in the bone neoformation process in tibia of rats.MATERIAL AND METHOD: 36 male rats (Rattus norvegicus) were used, divided into two groups of 18 rats each. Two circumferential bo...
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doaj-cddd73e3079e4fad843f6da1eb98c2e52020-11-25T00:33:48ZengUniversidade Estadual PaulistaRevista de Odontologia da UNESP1807-257743529930410.1590/rou.2014.048S1807-25772014000500299Aloe vera as vehicle to mineral trioxide aggregate: study in bone repairJessyca Leal Moura FÉCaroline de Araújo COELHOGermana Miranda DAMASCENAIsadora Mello Vilarinho SOARESFlávio Ribeiro ALVESÍsidra Manuela Sousa Portela SANTOSCarmen Milena Rodrigues Siqueira CARVALHOAIM: Mineral trioxide aggregate (MTA) was associated to Aloe vera to verify the coadjutant action of that medicinal plant in the bone neoformation process in tibia of rats.MATERIAL AND METHOD: 36 male rats (Rattus norvegicus) were used, divided into two groups of 18 rats each. Two circumferential bone defects with approximately 5 mm in diameter were made on the right tibia of each animal: the upper defect was filled with blood coagulates in both groups to serve as experimental control and the lower defect was filled with MTA and Aloe vera in experimental (group E1) and MTA and distilled water in experimental (group E2). Seven, 15 and 30 days after surgery, six animals from each group were euthanized and the right tibia of each animal was removed for histological analysis.RESULT: Histologically, experimental group E1 presented better results for the two variables, inflammation [at seven days (p=0.045)] and bone formation [at seven days (p=0.018) and 30 days (p=0.034)], compared to the E2 group.CONCLUSION: The association of MTA and Aloe vera showed potential to reduce the effects of the inflammatory cascade and promote bone neoformation making it to a promising proposal for future use in endodontic therapy.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-25772014000500299&lng=en&tlng=enBone regenerationphytotherapeutic drugsinflammationhistologyendodontics |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jessyca Leal Moura FÉ Caroline de Araújo COELHO Germana Miranda DAMASCENA Isadora Mello Vilarinho SOARES Flávio Ribeiro ALVES Ísidra Manuela Sousa Portela SANTOS Carmen Milena Rodrigues Siqueira CARVALHO |
spellingShingle |
Jessyca Leal Moura FÉ Caroline de Araújo COELHO Germana Miranda DAMASCENA Isadora Mello Vilarinho SOARES Flávio Ribeiro ALVES Ísidra Manuela Sousa Portela SANTOS Carmen Milena Rodrigues Siqueira CARVALHO Aloe vera as vehicle to mineral trioxide aggregate: study in bone repair Revista de Odontologia da UNESP Bone regeneration phytotherapeutic drugs inflammation histology endodontics |
author_facet |
Jessyca Leal Moura FÉ Caroline de Araújo COELHO Germana Miranda DAMASCENA Isadora Mello Vilarinho SOARES Flávio Ribeiro ALVES Ísidra Manuela Sousa Portela SANTOS Carmen Milena Rodrigues Siqueira CARVALHO |
author_sort |
Jessyca Leal Moura FÉ |
title |
Aloe vera as vehicle to mineral trioxide aggregate: study in bone repair |
title_short |
Aloe vera as vehicle to mineral trioxide aggregate: study in bone repair |
title_full |
Aloe vera as vehicle to mineral trioxide aggregate: study in bone repair |
title_fullStr |
Aloe vera as vehicle to mineral trioxide aggregate: study in bone repair |
title_full_unstemmed |
Aloe vera as vehicle to mineral trioxide aggregate: study in bone repair |
title_sort |
aloe vera as vehicle to mineral trioxide aggregate: study in bone repair |
publisher |
Universidade Estadual Paulista |
series |
Revista de Odontologia da UNESP |
issn |
1807-2577 |
description |
AIM: Mineral trioxide aggregate (MTA) was associated to Aloe vera to verify the coadjutant action of that medicinal plant in the bone neoformation process in tibia of rats.MATERIAL AND METHOD: 36 male rats (Rattus norvegicus) were used, divided into two groups of 18 rats each. Two circumferential bone defects with approximately 5 mm in diameter were made on the right tibia of each animal: the upper defect was filled with blood coagulates in both groups to serve as experimental control and the lower defect was filled with MTA and Aloe vera in experimental (group E1) and MTA and distilled water in experimental (group E2). Seven, 15 and 30 days after surgery, six animals from each group were euthanized and the right tibia of each animal was removed for histological analysis.RESULT: Histologically, experimental group E1 presented better results for the two variables, inflammation [at seven days (p=0.045)] and bone formation [at seven days (p=0.018) and 30 days (p=0.034)], compared to the E2 group.CONCLUSION: The association of MTA and Aloe vera showed potential to reduce the effects of the inflammatory cascade and promote bone neoformation making it to a promising proposal for future use in endodontic therapy. |
topic |
Bone regeneration phytotherapeutic drugs inflammation histology endodontics |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-25772014000500299&lng=en&tlng=en |
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