Bone morphogenetic protein 4 (BMP4) promotes hepatic glycogen accumulation and reduces glucose level in hepatocytes through mTORC2 signaling pathway

Bone morphogenetic protein 4 (BMP4) promotes hepatic glycogen accumulation and reduces glucose level in hepatocytes through mTORC2 signaling pathway

Liver is an important organ for regulating glucose and lipid metabolism. Recent studies have shown that bone morphogenetic proteins (BMPs) may play important roles in regulating glucose and lipid metabolism. In our previous studies, we demonstrated that BMP4 significantly inhibits hepatic steatosis...

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Bibliographic Details
Main Authors: Liqin An, Qiong Shi, Ying Zhu, Hao Wang, Qi Peng, Jinghong Wu, Yu Cheng, Wei Zhang, Yanyu Yi, Zihao Bao, Hui Zhang, Yetao Luo, Jiaming Fan
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Genes and Diseases
Subjects:
BMP4
Glucose metabolism
Glycogen accumulation
mTORC2 signaling
Non-alcoholic fatty liver disease (NAFLD)
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304220301355

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