A systemic evaluation of cardiac differentiation from mRNA reprogrammed human induced pluripotent stem cells.
Genetically unmodified cardiomyocytes mandated for cardiac regenerative therapy is conceivable by "foot-print free" reprogramming of somatic cells to induced pluripotent stem cells (iPSC). In this study, we report generation of foot-print free hiPSC through messenger RNA (mRNA) based repro...
Main Authors: | Ashish Mehta, Vinod Verma, Manasi Nandihalli, Chrishan J A Ramachandra, Glen L Sequiera, Yuliansa Sudibyo, Yingying Chung, William Sun, Winston Shim |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4113436?pdf=render |
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