Fetal and maternal factors are associated with mortality due to circulatory system disorders in children
ABSTRACT OBJECTIVE To analyze the association of characteristics recorded at the time of birth, including weight, occurrence of asphyxia, gestation duration, maternal age and education level, with death from diseases or malformations of the circulatory system in children under 18 years of age. ME...
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Universidade de São Paulo
2019-04-01
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doaj-ce07f5ed7c494cd880a391a07a563e0a2020-11-25T00:52:57ZengUniversidade de São PauloRevista de Saúde Pública1518-87872019-04-0153010.11606/s1518-8787.2019053000793S0034-89102019000100227Fetal and maternal factors are associated with mortality due to circulatory system disorders in childrenThais Rocha SalimGabriel Porto SoaresCarlos Henrique KleinGláucia Maria Moraes OliveiraABSTRACT OBJECTIVE To analyze the association of characteristics recorded at the time of birth, including weight, occurrence of asphyxia, gestation duration, maternal age and education level, with death from diseases or malformations of the circulatory system in children under 18 years of age. METHODS The Brazilian Information System on Live Births and Information System on Mortality databases were linked and evaluated following a longitudinal cohort analysis strategy. The following independent variables were evaluated: characteristics recorded at the time of birth, including weight, occurrence of asphyxia, gestation duration, maternal age and education level. Dependent variables were death from diseases or malformations of the circulatory system in children under 18 years of age. Crude relative risks were estimated and relative risks were adjusted for the variables. RESULTS 6,380 deaths were linked to 4,282,260 birth records, yielding 5,062 pairs considered as true. Low birth weight (RR = 2.26), asphyxia at 1 (RR = 1.72) and 5 minutes (RR = 1.51), prematurity (RR = 1.50), maternal age ≥ 40 years (RR = 2.06), and low maternal education level (RR = 1.45) increased the probability of death caused by circulatory system diseases. In the association with death by malformations of the circulatory system, the predictive variables showed the same association profile, but with greater intensity. CONCLUSIONS Fetal and maternal factors are associated with increased mortality due to diseases and malformations of the circulatory system. Measures to control these factors and improve access to their diagnosis and treatment would contribute to reducing the number of deaths caused by diseases and malformations of the circulatory system. However, the identification of environmental influences during gestation and birth on the risk of death should be carefully considered due to being influenced by genetic factors.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102019000100227&lng=en&tlng=enChildAdolescentCardiovascular Diseases, mortalityVascular Malformations, mortalityHeart Defects, Congenital, mortalityRisk factorsInfant, PrematureAsphyxia NeonatorumMaternal Health |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Thais Rocha Salim Gabriel Porto Soares Carlos Henrique Klein Gláucia Maria Moraes Oliveira |
spellingShingle |
Thais Rocha Salim Gabriel Porto Soares Carlos Henrique Klein Gláucia Maria Moraes Oliveira Fetal and maternal factors are associated with mortality due to circulatory system disorders in children Revista de Saúde Pública Child Adolescent Cardiovascular Diseases, mortality Vascular Malformations, mortality Heart Defects, Congenital, mortality Risk factors Infant, Premature Asphyxia Neonatorum Maternal Health |
author_facet |
Thais Rocha Salim Gabriel Porto Soares Carlos Henrique Klein Gláucia Maria Moraes Oliveira |
author_sort |
Thais Rocha Salim |
title |
Fetal and maternal factors are associated with mortality due to circulatory system disorders in children |
title_short |
Fetal and maternal factors are associated with mortality due to circulatory system disorders in children |
title_full |
Fetal and maternal factors are associated with mortality due to circulatory system disorders in children |
title_fullStr |
Fetal and maternal factors are associated with mortality due to circulatory system disorders in children |
title_full_unstemmed |
Fetal and maternal factors are associated with mortality due to circulatory system disorders in children |
title_sort |
fetal and maternal factors are associated with mortality due to circulatory system disorders in children |
publisher |
Universidade de São Paulo |
series |
Revista de Saúde Pública |
issn |
1518-8787 |
publishDate |
2019-04-01 |
description |
ABSTRACT OBJECTIVE To analyze the association of characteristics recorded at the time of birth, including weight, occurrence of asphyxia, gestation duration, maternal age and education level, with death from diseases or malformations of the circulatory system in children under 18 years of age. METHODS The Brazilian Information System on Live Births and Information System on Mortality databases were linked and evaluated following a longitudinal cohort analysis strategy. The following independent variables were evaluated: characteristics recorded at the time of birth, including weight, occurrence of asphyxia, gestation duration, maternal age and education level. Dependent variables were death from diseases or malformations of the circulatory system in children under 18 years of age. Crude relative risks were estimated and relative risks were adjusted for the variables. RESULTS 6,380 deaths were linked to 4,282,260 birth records, yielding 5,062 pairs considered as true. Low birth weight (RR = 2.26), asphyxia at 1 (RR = 1.72) and 5 minutes (RR = 1.51), prematurity (RR = 1.50), maternal age ≥ 40 years (RR = 2.06), and low maternal education level (RR = 1.45) increased the probability of death caused by circulatory system diseases. In the association with death by malformations of the circulatory system, the predictive variables showed the same association profile, but with greater intensity. CONCLUSIONS Fetal and maternal factors are associated with increased mortality due to diseases and malformations of the circulatory system. Measures to control these factors and improve access to their diagnosis and treatment would contribute to reducing the number of deaths caused by diseases and malformations of the circulatory system. However, the identification of environmental influences during gestation and birth on the risk of death should be carefully considered due to being influenced by genetic factors. |
topic |
Child Adolescent Cardiovascular Diseases, mortality Vascular Malformations, mortality Heart Defects, Congenital, mortality Risk factors Infant, Premature Asphyxia Neonatorum Maternal Health |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102019000100227&lng=en&tlng=en |
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