Berberine Could Ameliorate Cardiac Dysfunction via Interfering Myocardial Lipidomic Profiles in the Rat Model of Diabetic Cardiomyopathy

Berberine Could Ameliorate Cardiac Dysfunction via Interfering Myocardial Lipidomic Profiles in the Rat Model of Diabetic Cardiomyopathy

Background: Diabetic cardiomyopathy (DCM) is considered to be a distinct clinical entity independent of concomitant macro- and microvascular disorders, which is initiated partly by disturbances in energy substrates. This study was to observe the dynamic modulations of berberine in DCM rats and explo...

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Bibliographic Details
Main Authors: Shifen Dong, Shuofeng Zhang, Zhirong Chen, Rong Zhang, Linyue Tian, Long Cheng, Fei Shang, Jianning Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Physiology
Subjects:
diabetic cardiomyopathy
myocardial tissue
lipidomic profiles
berberine
UPLC/Q-TOF/MS
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.01042/full

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