A game-theoretic approach to deciphering the dynamics of amyloid-β aggregation along competing pathways

Aggregation of amyloid-β (Aβ) peptides is a significant event that underpins Alzheimer's disease (AD). Aβ aggregates, especially the low-molecular weight oligomers, are the primary toxic agents in AD pathogenesis. Therefore, there is increasing interest in understanding their formation and beha...

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Bibliographic Details
Main Authors: Preetam Ghosh, Pratip Rana, Vijayaraghavan Rangachari, Jhinuk Saha, Edward Steen, Ashwin Vaidya
Format: Article
Language:English
Published: The Royal Society 2020-04-01
Series:Royal Society Open Science
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.191814