FBXO17 promotes cell proliferation through activation of Akt in lung adenocarcinoma cells

FBXO17 promotes cell proliferation through activation of Akt in lung adenocarcinoma cells

Abstract Background The ubiquitin-proteasome pathway, mediated in part, by ubiquitin E3 ligases, is critical in regulating cellular processes such as cell proliferation, apoptosis, and migration. FBXO17 was recently identified as an F-box protein that targets glycogen synthase kinase-3β to the E3 ub...

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Bibliographic Details
Main Authors: Tomeka L. Suber, Ina Nikolli, Michael E. O’Brien, James Londino, Jing Zhao, Kong Chen, Rama K. Mallampalli, Yutong Zhao
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Respiratory Research
Subjects:
Akt
FBXO17
Proliferation
Lung cancer
Online Access:http://link.springer.com/article/10.1186/s12931-018-0910-0

Internet

http://link.springer.com/article/10.1186/s12931-018-0910-0

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