Vitamin D and Reproduction: From Gametes to Childhood
Vitamin D is well recognized for its essentiality in maintaining skeletal health. Recent research has suggested that vitamin D may exert a broad range of roles throughout the human life cycle starting from reproduction to adult chronic disease risk. Rates of vitamin D deficiency during pregnancy rem...
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doaj-ce3933a5f392460798e1796f57e4ca1b2020-11-24T23:29:24ZengMDPI AGHealthcare2227-90322015-11-01341097112010.3390/healthcare3041097healthcare3041097Vitamin D and Reproduction: From Gametes to ChildhoodKrista D. Sowell0Carl L. Keen1Janet Y. Uriu-Adams2Department of Nutrition, University of California, Davis, One Shields Avenue, Davis, CA 95616, USADepartment of Nutrition, University of California, Davis, One Shields Avenue, Davis, CA 95616, USADepartment of Nutrition, University of California, Davis, One Shields Avenue, Davis, CA 95616, USAVitamin D is well recognized for its essentiality in maintaining skeletal health. Recent research has suggested that vitamin D may exert a broad range of roles throughout the human life cycle starting from reproduction to adult chronic disease risk. Rates of vitamin D deficiency during pregnancy remain high worldwide. Vitamin D deficiency has been associated with an increased risk of fertility problems, preeclampsia, gestational diabetes, and allergic disease in the offspring. Vitamin D is found naturally in only a few foods thus supplementation can provide an accessible and effective way to raise vitamin D status when dietary intakes and sunlight exposure are low. However, the possibility of overconsumption and possible adverse effects is under debate. The effect of vitamin D supplementation during pregnancy and early life on maternal and infant outcomes will be of particular focus in this review.http://www.mdpi.com/2227-9032/3/4/1097vitamin Dvitamin D supplementationpregnancyfertilitytoxicitypreeclampsiagestational diabetesallergic disease |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Krista D. Sowell Carl L. Keen Janet Y. Uriu-Adams |
spellingShingle |
Krista D. Sowell Carl L. Keen Janet Y. Uriu-Adams Vitamin D and Reproduction: From Gametes to Childhood Healthcare vitamin D vitamin D supplementation pregnancy fertility toxicity preeclampsia gestational diabetes allergic disease |
author_facet |
Krista D. Sowell Carl L. Keen Janet Y. Uriu-Adams |
author_sort |
Krista D. Sowell |
title |
Vitamin D and Reproduction: From Gametes to Childhood |
title_short |
Vitamin D and Reproduction: From Gametes to Childhood |
title_full |
Vitamin D and Reproduction: From Gametes to Childhood |
title_fullStr |
Vitamin D and Reproduction: From Gametes to Childhood |
title_full_unstemmed |
Vitamin D and Reproduction: From Gametes to Childhood |
title_sort |
vitamin d and reproduction: from gametes to childhood |
publisher |
MDPI AG |
series |
Healthcare |
issn |
2227-9032 |
publishDate |
2015-11-01 |
description |
Vitamin D is well recognized for its essentiality in maintaining skeletal health. Recent research has suggested that vitamin D may exert a broad range of roles throughout the human life cycle starting from reproduction to adult chronic disease risk. Rates of vitamin D deficiency during pregnancy remain high worldwide. Vitamin D deficiency has been associated with an increased risk of fertility problems, preeclampsia, gestational diabetes, and allergic disease in the offspring. Vitamin D is found naturally in only a few foods thus supplementation can provide an accessible and effective way to raise vitamin D status when dietary intakes and sunlight exposure are low. However, the possibility of overconsumption and possible adverse effects is under debate. The effect of vitamin D supplementation during pregnancy and early life on maternal and infant outcomes will be of particular focus in this review. |
topic |
vitamin D vitamin D supplementation pregnancy fertility toxicity preeclampsia gestational diabetes allergic disease |
url |
http://www.mdpi.com/2227-9032/3/4/1097 |
work_keys_str_mv |
AT kristadsowell vitamindandreproductionfromgametestochildhood AT carllkeen vitamindandreproductionfromgametestochildhood AT janetyuriuadams vitamindandreproductionfromgametestochildhood |
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1725545840925212672 |