Polysaccharide-Based Biomaterials for Protein Delivery

Micro- and nanotechnology-based carriers for protein delivery are continuously being developed and refined. Their advantages for protein therapeutics include enhanced bioavailability, stability, and permeability and reduced immunogenicity. Natural polysaccharides have aroused widespread interest in...

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Main Authors:	Kaili Wang, Mingqi Liu, Ran Mo
Format:	Article
Language:	English
Published:	Elsevier 2020-09-01
Series:	Medicine in Drug Discovery
Subjects:	drug delivery biomaterials protein polysaccharides micro-nanocarriers functionalization
Online Access:	http://www.sciencedirect.com/science/article/pii/S259009862030018X

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record_format	Article
spelling	doaj-ce477ed48bb04e41a04fc4e3b0e9ec5f2020-11-25T04:03:53ZengElsevierMedicine in Drug Discovery2590-09862020-09-017100031Polysaccharide-Based Biomaterials for Protein DeliveryKaili Wang0Mingqi Liu1Ran Mo2State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, Center of Advanced Pharmaceuticals and Biomaterials, China Pharmaceutical University, Nanjing 210009, ChinaState Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, Center of Advanced Pharmaceuticals and Biomaterials, China Pharmaceutical University, Nanjing 210009, ChinaCorresponding author.; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, Center of Advanced Pharmaceuticals and Biomaterials, China Pharmaceutical University, Nanjing 210009, ChinaMicro- and nanotechnology-based carriers for protein delivery are continuously being developed and refined. Their advantages for protein therapeutics include enhanced bioavailability, stability, and permeability and reduced immunogenicity. Natural polysaccharides have aroused widespread interest in protein delivery systems due to their superior biocompatibility, low immunogenicity, and abundance. In this review, we survey recent advances in microcarriers and nanocarriers using biomaterials and formulations derived from natural polysaccharides. Potential applications and challenges for future development are also discussed.http://www.sciencedirect.com/science/article/pii/S259009862030018Xdrug deliverybiomaterialsproteinpolysaccharidesmicro-nanocarriersfunctionalization
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Kaili Wang Mingqi Liu Ran Mo
spellingShingle	Kaili Wang Mingqi Liu Ran Mo Polysaccharide-Based Biomaterials for Protein Delivery Medicine in Drug Discovery drug delivery biomaterials protein polysaccharides micro-nanocarriers functionalization
author_facet	Kaili Wang Mingqi Liu Ran Mo
author_sort	Kaili Wang
title	Polysaccharide-Based Biomaterials for Protein Delivery
title_short	Polysaccharide-Based Biomaterials for Protein Delivery
title_full	Polysaccharide-Based Biomaterials for Protein Delivery
title_fullStr	Polysaccharide-Based Biomaterials for Protein Delivery
title_full_unstemmed	Polysaccharide-Based Biomaterials for Protein Delivery
title_sort	polysaccharide-based biomaterials for protein delivery
publisher	Elsevier
series	Medicine in Drug Discovery
issn	2590-0986
publishDate	2020-09-01
description	Micro- and nanotechnology-based carriers for protein delivery are continuously being developed and refined. Their advantages for protein therapeutics include enhanced bioavailability, stability, and permeability and reduced immunogenicity. Natural polysaccharides have aroused widespread interest in protein delivery systems due to their superior biocompatibility, low immunogenicity, and abundance. In this review, we survey recent advances in microcarriers and nanocarriers using biomaterials and formulations derived from natural polysaccharides. Potential applications and challenges for future development are also discussed.
topic	drug delivery biomaterials protein polysaccharides micro-nanocarriers functionalization
url	http://www.sciencedirect.com/science/article/pii/S259009862030018X
work_keys_str_mv	AT kailiwang polysaccharidebasedbiomaterialsforproteindelivery AT mingqiliu polysaccharidebasedbiomaterialsforproteindelivery AT ranmo polysaccharidebasedbiomaterialsforproteindelivery
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Polysaccharide-Based Biomaterials for Protein Delivery

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