Polysaccharide-Based Biomaterials for Protein Delivery
Micro- and nanotechnology-based carriers for protein delivery are continuously being developed and refined. Their advantages for protein therapeutics include enhanced bioavailability, stability, and permeability and reduced immunogenicity. Natural polysaccharides have aroused widespread interest in...
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2020-09-01
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doaj-ce477ed48bb04e41a04fc4e3b0e9ec5f2020-11-25T04:03:53ZengElsevierMedicine in Drug Discovery2590-09862020-09-017100031Polysaccharide-Based Biomaterials for Protein DeliveryKaili Wang0Mingqi Liu1Ran Mo2State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, Center of Advanced Pharmaceuticals and Biomaterials, China Pharmaceutical University, Nanjing 210009, ChinaState Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, Center of Advanced Pharmaceuticals and Biomaterials, China Pharmaceutical University, Nanjing 210009, ChinaCorresponding author.; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, Center of Advanced Pharmaceuticals and Biomaterials, China Pharmaceutical University, Nanjing 210009, ChinaMicro- and nanotechnology-based carriers for protein delivery are continuously being developed and refined. Their advantages for protein therapeutics include enhanced bioavailability, stability, and permeability and reduced immunogenicity. Natural polysaccharides have aroused widespread interest in protein delivery systems due to their superior biocompatibility, low immunogenicity, and abundance. In this review, we survey recent advances in microcarriers and nanocarriers using biomaterials and formulations derived from natural polysaccharides. Potential applications and challenges for future development are also discussed.http://www.sciencedirect.com/science/article/pii/S259009862030018Xdrug deliverybiomaterialsproteinpolysaccharidesmicro-nanocarriersfunctionalization |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Kaili Wang Mingqi Liu Ran Mo |
spellingShingle |
Kaili Wang Mingqi Liu Ran Mo Polysaccharide-Based Biomaterials for Protein Delivery Medicine in Drug Discovery drug delivery biomaterials protein polysaccharides micro-nanocarriers functionalization |
author_facet |
Kaili Wang Mingqi Liu Ran Mo |
author_sort |
Kaili Wang |
title |
Polysaccharide-Based Biomaterials for Protein Delivery |
title_short |
Polysaccharide-Based Biomaterials for Protein Delivery |
title_full |
Polysaccharide-Based Biomaterials for Protein Delivery |
title_fullStr |
Polysaccharide-Based Biomaterials for Protein Delivery |
title_full_unstemmed |
Polysaccharide-Based Biomaterials for Protein Delivery |
title_sort |
polysaccharide-based biomaterials for protein delivery |
publisher |
Elsevier |
series |
Medicine in Drug Discovery |
issn |
2590-0986 |
publishDate |
2020-09-01 |
description |
Micro- and nanotechnology-based carriers for protein delivery are continuously being developed and refined. Their advantages for protein therapeutics include enhanced bioavailability, stability, and permeability and reduced immunogenicity. Natural polysaccharides have aroused widespread interest in protein delivery systems due to their superior biocompatibility, low immunogenicity, and abundance. In this review, we survey recent advances in microcarriers and nanocarriers using biomaterials and formulations derived from natural polysaccharides. Potential applications and challenges for future development are also discussed. |
topic |
drug delivery biomaterials protein polysaccharides micro-nanocarriers functionalization |
url |
http://www.sciencedirect.com/science/article/pii/S259009862030018X |
work_keys_str_mv |
AT kailiwang polysaccharidebasedbiomaterialsforproteindelivery AT mingqiliu polysaccharidebasedbiomaterialsforproteindelivery AT ranmo polysaccharidebasedbiomaterialsforproteindelivery |
_version_ |
1724438665981067264 |