Development and Validation of Persian Risk Assessment Tool using National Comprehensive Cancer Network Guideline for Colorectal Cancer Screening

• Main Authors: Roya Dolatkhah, Saeed Dastgiri, Mohammad Asghari Jafarabadi, Hossein Mashhadi Abdolahi, Bita Sepehri, Masoud Shirmohammadi, Faris Farassati, Mohammad Hossein Somi
• Format: Article
• Language: English
• Published: JCDR Research and Publications Private Limited 2020-01-01
• Series: Journal of Clinical and Diagnostic Research
• Subjects: content validity index; content validity ratio; questionnaire
• Online Access: https://jcdr.net/articles/PDF/13433/42726_F(SL)_CE[Ra1]_(SL)_PF1(AJ_SHU)_PFA(AJ_SHU)_PN(SL).pdf

Introduction: Despite evidence that early diagnosis of Colorectal Cancer (CRC) reduces the associated death burden, screening programs are uncommon even in developed countries. Aim: To develop and validate a simple, practical and efficient tool to improve CRC risk assessment by identifying moderateand high-risk disease. Materials and Methods: The National Comprehensive Cancer Network guideline has been used to develop the CRC risk assessment tool. Content validity was assessed by a panel of 10 experts by generating a Content Validity Index (CVI), which was recorded quantitatively as the proportion of experts who agreed that the item was relevant, before calculating the Content Validity Ratio (CVR) per item. Results: The CVI was in the range 0.7-1 and the acceptable CVR was in the range 0.4-1. The overall mean CVI and CVR values were 0.93 and 0.62, respectively. Changes were made according to the experts’ recommendations, and the final online Persian questionnaire was assessed for face validity by 15 individuals (general population voluntarily). Only a few items subsequently needed modification and expansion. Conclusion: The Persian Risk Assessment tool is simple, quick, and easy to apply to different clinical categories and subcategories of CRC and can even be self-administered. This is the first translated tool in Persian version, usable in Iran.