The machinery underlying malaria parasite virulence is conserved between rodent and human malaria parasites
Proteins SBP1 and MAHRP1 of the human malaria parasite are required for sequestration of infected red blood cells in major organs. Here, De Niz et al. identify homologous proteins in the rodent parasite Plasmodium berghei, showing that they play similar roles and supporting the usefulness of malaria...
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Nature Publishing Group
2016-05-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms11659 |
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doaj-ce5dde75c34e4b5ebcf04a7b660268c82021-05-11T10:51:22ZengNature Publishing GroupNature Communications2041-17232016-05-017111210.1038/ncomms11659The machinery underlying malaria parasite virulence is conserved between rodent and human malaria parasitesMariana De Niz0Ann-Katrin Ullrich1Arlett Heiber2Alexandra Blancke Soares3Christian Pick4Ruth Lyck5Derya Keller6Gesine Kaiser7Monica Prado8Sven Flemming9Hernando del Portillo10Chris J. Janse11Volker Heussler12Tobias Spielmann13Institute of Cell Biology, University of BernBernhard Nocht Institute for Tropical Medicine, Parasitology SectionBernhard Nocht Institute for Tropical Medicine, Parasitology SectionBernhard Nocht Institute for Tropical Medicine, Parasitology SectionInstitute of Zoology, Universtity of HamburgTheodor Kocher Institute, University of BernInstitute of Cell Biology, University of BernInstitute of Cell Biology, University of BernBernhard Nocht Institute for Tropical Medicine, Parasitology SectionBernhard Nocht Institute for Tropical Medicine, Parasitology SectionICREA at ISGlobal, Barcelona Ctr. Int. Health Res. (CRESIB), Hospital Clínic—Universitat de Barcelona and Institut d’Investigació Germans Trias i Pujol (IGTP). Ctra. de Can Ruti. Camí de les Escoles, s/nDepartment of Parasitology, Leiden Malaria Research Group, Leiden University Medical CenterInstitute of Cell Biology, University of BernBernhard Nocht Institute for Tropical Medicine, Parasitology SectionProteins SBP1 and MAHRP1 of the human malaria parasite are required for sequestration of infected red blood cells in major organs. Here, De Niz et al. identify homologous proteins in the rodent parasite Plasmodium berghei, showing that they play similar roles and supporting the usefulness of malaria mouse models.https://doi.org/10.1038/ncomms11659 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Mariana De Niz Ann-Katrin Ullrich Arlett Heiber Alexandra Blancke Soares Christian Pick Ruth Lyck Derya Keller Gesine Kaiser Monica Prado Sven Flemming Hernando del Portillo Chris J. Janse Volker Heussler Tobias Spielmann |
| spellingShingle |
Mariana De Niz Ann-Katrin Ullrich Arlett Heiber Alexandra Blancke Soares Christian Pick Ruth Lyck Derya Keller Gesine Kaiser Monica Prado Sven Flemming Hernando del Portillo Chris J. Janse Volker Heussler Tobias Spielmann The machinery underlying malaria parasite virulence is conserved between rodent and human malaria parasites Nature Communications |
| author_facet |
Mariana De Niz Ann-Katrin Ullrich Arlett Heiber Alexandra Blancke Soares Christian Pick Ruth Lyck Derya Keller Gesine Kaiser Monica Prado Sven Flemming Hernando del Portillo Chris J. Janse Volker Heussler Tobias Spielmann |
| author_sort |
Mariana De Niz |
| title |
The machinery underlying malaria parasite virulence is conserved between rodent and human malaria parasites |
| title_short |
The machinery underlying malaria parasite virulence is conserved between rodent and human malaria parasites |
| title_full |
The machinery underlying malaria parasite virulence is conserved between rodent and human malaria parasites |
| title_fullStr |
The machinery underlying malaria parasite virulence is conserved between rodent and human malaria parasites |
| title_full_unstemmed |
The machinery underlying malaria parasite virulence is conserved between rodent and human malaria parasites |
| title_sort |
machinery underlying malaria parasite virulence is conserved between rodent and human malaria parasites |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2016-05-01 |
| description |
Proteins SBP1 and MAHRP1 of the human malaria parasite are required for sequestration of infected red blood cells in major organs. Here, De Niz et al. identify homologous proteins in the rodent parasite Plasmodium berghei, showing that they play similar roles and supporting the usefulness of malaria mouse models. |
| url |
https://doi.org/10.1038/ncomms11659 |
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