Construction of the descriptive system for the assessment of quality of life AQoL-6D utility instrument
<p>Abstract</p> <p>Background</p> <p>Multi attribute utility (MAU) instruments are used to include the health related quality of life (HRQoL) in economic evaluations of health programs. Comparative studies suggest different MAU instruments measure related but different...
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doaj-ce69d23ef437414bb10439d469248fab2020-11-24T21:52:49ZengBMCHealth and Quality of Life Outcomes1477-75252012-04-011013810.1186/1477-7525-10-38Construction of the descriptive system for the assessment of quality of life AQoL-6D utility instrumentRichardson Jeffrey RJPeacock Stuart JHawthorne GraemeIezzi AngeloElsworth GeraldDay Neil A<p>Abstract</p> <p>Background</p> <p>Multi attribute utility (MAU) instruments are used to include the health related quality of life (HRQoL) in economic evaluations of health programs. Comparative studies suggest different MAU instruments measure related but different constructs. The objective of this paper is to describe the methods employed to achieve content validity in the descriptive system of the Assessment of Quality of Life (AQoL)-6D, MAU instrument.</p> <p>Methods</p> <p>The AQoL program introduced the use of psychometric methods in the construction of health related MAU instruments. To develop the AQoL-6D we selected 112 items from previous research, focus groups and expert judgment and administered them to 316 members of the public and 302 hospital patients. The search for content validity across a broad spectrum of health states required both formative and reflective modelling. We employed Exploratory Factor Analysis and Structural Equation Modelling (SEM) to meet these dual requirements.</p> <p>Results and Discussion</p> <p>The resulting instrument employs 20 items in a multi-tier descriptive system. Latent dimension variables achieve sensitive descriptions of 6 dimensions which, in turn, combine to form a single latent QoL variable. Diagnostic statistics from the SEM analysis are exceptionally good and confirm the hypothesised structure of the model.</p> <p>Conclusions</p> <p>The AQoL-6D descriptive system has good psychometric properties. They imply that the instrument has achieved construct validity and provides a sensitive description of HRQoL. This means that it may be used with confidence for measuring health related quality of life and that it is a suitable basis for modelling utilities for inclusion in the economic evaluation of health programs.</p> http://www.hqlo.com/content/10/1/38Quality of LifeMAU instrumentHRQoLEconomic evaluation |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Richardson Jeffrey RJ Peacock Stuart J Hawthorne Graeme Iezzi Angelo Elsworth Gerald Day Neil A |
spellingShingle |
Richardson Jeffrey RJ Peacock Stuart J Hawthorne Graeme Iezzi Angelo Elsworth Gerald Day Neil A Construction of the descriptive system for the assessment of quality of life AQoL-6D utility instrument Health and Quality of Life Outcomes Quality of Life MAU instrument HRQoL Economic evaluation |
author_facet |
Richardson Jeffrey RJ Peacock Stuart J Hawthorne Graeme Iezzi Angelo Elsworth Gerald Day Neil A |
author_sort |
Richardson Jeffrey RJ |
title |
Construction of the descriptive system for the assessment of quality of life AQoL-6D utility instrument |
title_short |
Construction of the descriptive system for the assessment of quality of life AQoL-6D utility instrument |
title_full |
Construction of the descriptive system for the assessment of quality of life AQoL-6D utility instrument |
title_fullStr |
Construction of the descriptive system for the assessment of quality of life AQoL-6D utility instrument |
title_full_unstemmed |
Construction of the descriptive system for the assessment of quality of life AQoL-6D utility instrument |
title_sort |
construction of the descriptive system for the assessment of quality of life aqol-6d utility instrument |
publisher |
BMC |
series |
Health and Quality of Life Outcomes |
issn |
1477-7525 |
publishDate |
2012-04-01 |
description |
<p>Abstract</p> <p>Background</p> <p>Multi attribute utility (MAU) instruments are used to include the health related quality of life (HRQoL) in economic evaluations of health programs. Comparative studies suggest different MAU instruments measure related but different constructs. The objective of this paper is to describe the methods employed to achieve content validity in the descriptive system of the Assessment of Quality of Life (AQoL)-6D, MAU instrument.</p> <p>Methods</p> <p>The AQoL program introduced the use of psychometric methods in the construction of health related MAU instruments. To develop the AQoL-6D we selected 112 items from previous research, focus groups and expert judgment and administered them to 316 members of the public and 302 hospital patients. The search for content validity across a broad spectrum of health states required both formative and reflective modelling. We employed Exploratory Factor Analysis and Structural Equation Modelling (SEM) to meet these dual requirements.</p> <p>Results and Discussion</p> <p>The resulting instrument employs 20 items in a multi-tier descriptive system. Latent dimension variables achieve sensitive descriptions of 6 dimensions which, in turn, combine to form a single latent QoL variable. Diagnostic statistics from the SEM analysis are exceptionally good and confirm the hypothesised structure of the model.</p> <p>Conclusions</p> <p>The AQoL-6D descriptive system has good psychometric properties. They imply that the instrument has achieved construct validity and provides a sensitive description of HRQoL. This means that it may be used with confidence for measuring health related quality of life and that it is a suitable basis for modelling utilities for inclusion in the economic evaluation of health programs.</p> |
topic |
Quality of Life MAU instrument HRQoL Economic evaluation |
url |
http://www.hqlo.com/content/10/1/38 |
work_keys_str_mv |
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