Five New Phenolic Compounds with Antioxidant Activities from the Medicinal Insect Blaps rynchopetera

Five New Phenolic Compounds with Antioxidant Activities from the Medicinal Insect Blaps rynchopetera

Five new phenolic compounds rynchopeterines A–E (1–5), in addition to thirteen known phenolics, were isolated from Blaps rynchopetera Fairmaire, a kind of medicinal insect utilized by the Yi Nationality in Yunnan Province of China. Their structures were established on the basis of extensive spectros...

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Bibliographic Details
Main Authors: Huai Xiao, Tian-Peng Yin, Jian-Wei Dong, Xiu-Mei Wu, Qing Luo, Jian-Rong Luo, Le Cai, Zhong-Tao Ding
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:Molecules
Subjects:
Blaps rynchopetera
chemical constituents
phenolic
rynchopeterines A–E
antioxidant
anti-tumor
Online Access:https://www.mdpi.com/1420-3049/22/8/1301
Description
Summary:Five new phenolic compounds rynchopeterines A–E (1–5), in addition to thirteen known phenolics, were isolated from Blaps rynchopetera Fairmaire, a kind of medicinal insect utilized by the Yi Nationality in Yunnan Province of China. Their structures were established on the basis of extensive spectroscopic analyses (1D and 2D NMR, HR-MS, IR) along with calculated electronic circular dichroism method. Rynchopeterines A–E (1–4) exhibited significant antioxidant activities with IC50 values of 7.67–12.3 μg/mL measured by the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. Besides, rynchopeterines B (2) and C (3) showed mild cytotoxicity against tumor cell Caco-2 and A549.
ISSN:1420-3049

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