An LC Wireless Microfluidic Sensor Based on Low Temperature Co-Fired Ceramic (LTCC) Technology

This work reports a novel wireless microfluidic biosensor based on low temperature co-fired ceramic (LTCC) technology. The wireless biosensor consists of a planar spiral inductor and parallel plate capacitor (LC) resonant antenna, which integrates with microchannel bends in the LTCC substrate. The w...

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Main Authors: Yongyuan Liang, Mingsheng Ma, Faqiang Zhang, Feng Liu, Zhifu Liu, Dong Wang, Yongxiang Li
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/19/5/1189
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spelling doaj-ce776d5525ae422b8bcfda85d5de901f2020-11-24T21:26:41ZengMDPI AGSensors1424-82202019-03-01195118910.3390/s19051189s19051189An LC Wireless Microfluidic Sensor Based on Low Temperature Co-Fired Ceramic (LTCC) TechnologyYongyuan Liang0Mingsheng Ma1Faqiang Zhang2Feng Liu3Zhifu Liu4Dong Wang5Yongxiang Li6CAS Key Laboratory of Inorganic Functional Materials and Devices, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, ChinaCAS Key Laboratory of Inorganic Functional Materials and Devices, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, ChinaCAS Key Laboratory of Inorganic Functional Materials and Devices, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, ChinaCAS Key Laboratory of Inorganic Functional Materials and Devices, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, ChinaCAS Key Laboratory of Inorganic Functional Materials and Devices, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, ChinaCAS Key Laboratory of Inorganic Functional Materials and Devices, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, ChinaSchool of Engineering, RMIT University, Melbourne VIC 3001, AustraliaThis work reports a novel wireless microfluidic biosensor based on low temperature co-fired ceramic (LTCC) technology. The wireless biosensor consists of a planar spiral inductor and parallel plate capacitor (LC) resonant antenna, which integrates with microchannel bends in the LTCC substrate. The wireless response of the biosensor was associated to the changes of its resonant frequency due to the alteration in the permittivity of the liquid flow in the microchannel. The wireless sensing performance to different organic liquids with permittivity from 3 to 78.5 was presented. The measured results are in good agreement with the theoretical calculation. The wireless detection for the concentration of glucose in water solution was investigated, and an excellent linear response and repeatability were obtained. This kind of LC wireless microfluidic sensor is very promising in establishing wireless lab-on-a-chip for biomedical and chemical applications.http://www.mdpi.com/1424-8220/19/5/1189microfluidicsLTCCwireless sensorliquid sensing
collection DOAJ
language English
format Article
sources DOAJ
author Yongyuan Liang
Mingsheng Ma
Faqiang Zhang
Feng Liu
Zhifu Liu
Dong Wang
Yongxiang Li
spellingShingle Yongyuan Liang
Mingsheng Ma
Faqiang Zhang
Feng Liu
Zhifu Liu
Dong Wang
Yongxiang Li
An LC Wireless Microfluidic Sensor Based on Low Temperature Co-Fired Ceramic (LTCC) Technology
Sensors
microfluidics
LTCC
wireless sensor
liquid sensing
author_facet Yongyuan Liang
Mingsheng Ma
Faqiang Zhang
Feng Liu
Zhifu Liu
Dong Wang
Yongxiang Li
author_sort Yongyuan Liang
title An LC Wireless Microfluidic Sensor Based on Low Temperature Co-Fired Ceramic (LTCC) Technology
title_short An LC Wireless Microfluidic Sensor Based on Low Temperature Co-Fired Ceramic (LTCC) Technology
title_full An LC Wireless Microfluidic Sensor Based on Low Temperature Co-Fired Ceramic (LTCC) Technology
title_fullStr An LC Wireless Microfluidic Sensor Based on Low Temperature Co-Fired Ceramic (LTCC) Technology
title_full_unstemmed An LC Wireless Microfluidic Sensor Based on Low Temperature Co-Fired Ceramic (LTCC) Technology
title_sort lc wireless microfluidic sensor based on low temperature co-fired ceramic (ltcc) technology
publisher MDPI AG
series Sensors
issn 1424-8220
publishDate 2019-03-01
description This work reports a novel wireless microfluidic biosensor based on low temperature co-fired ceramic (LTCC) technology. The wireless biosensor consists of a planar spiral inductor and parallel plate capacitor (LC) resonant antenna, which integrates with microchannel bends in the LTCC substrate. The wireless response of the biosensor was associated to the changes of its resonant frequency due to the alteration in the permittivity of the liquid flow in the microchannel. The wireless sensing performance to different organic liquids with permittivity from 3 to 78.5 was presented. The measured results are in good agreement with the theoretical calculation. The wireless detection for the concentration of glucose in water solution was investigated, and an excellent linear response and repeatability were obtained. This kind of LC wireless microfluidic sensor is very promising in establishing wireless lab-on-a-chip for biomedical and chemical applications.
topic microfluidics
LTCC
wireless sensor
liquid sensing
url http://www.mdpi.com/1424-8220/19/5/1189
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