Two Cerebrosides Isolated from the Seeds of Sterculia lychnophora and Their Neuroprotective Effect

Two cerebrosides named 1-O-b-D-glucopyranosyl-(2S,3R,4E,8Z)-2-[(2-hydroxyoctadecanoyl)amido]-4,8-octadecadiene-1,3-diol (1) and soya-cerebroside I (2) were isolated from the seeds of Sterculia lychnophora for the first time. Their structures were completely characterized by spectroscopic methods inc...

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Main Authors: Di Geng, Xiu-Wen Wu, Ru-Feng Wang
Format: Article
Language:English
Published: MDPI AG 2013-01-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/18/1/1181
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spelling doaj-ce793405157e4e009cfb9dda8dc73f922020-11-24T23:40:51ZengMDPI AGMolecules1420-30492013-01-011811181118710.3390/molecules18011181Two Cerebrosides Isolated from the Seeds of Sterculia lychnophora and Their Neuroprotective EffectDi GengXiu-Wen WuRu-Feng WangTwo cerebrosides named 1-O-b-D-glucopyranosyl-(2S,3R,4E,8Z)-2-[(2-hydroxyoctadecanoyl)amido]-4,8-octadecadiene-1,3-diol (1) and soya-cerebroside I (2) were isolated from the seeds of Sterculia lychnophora for the first time. Their structures were completely characterized by spectroscopic methods including IR, MS and NMR. Compound 1 exhibited moderate neuroprotective effect against SH-SY5Y cell damage induced by hydrogen peroxide.http://www.mdpi.com/1420-3049/18/1/1181Sterculia lychnophoraconstituentscerebrosidesneuroprotective effect
collection DOAJ
language English
format Article
sources DOAJ
author Di Geng
Xiu-Wen Wu
Ru-Feng Wang
spellingShingle Di Geng
Xiu-Wen Wu
Ru-Feng Wang
Two Cerebrosides Isolated from the Seeds of Sterculia lychnophora and Their Neuroprotective Effect
Molecules
Sterculia lychnophora
constituents
cerebrosides
neuroprotective effect
author_facet Di Geng
Xiu-Wen Wu
Ru-Feng Wang
author_sort Di Geng
title Two Cerebrosides Isolated from the Seeds of Sterculia lychnophora and Their Neuroprotective Effect
title_short Two Cerebrosides Isolated from the Seeds of Sterculia lychnophora and Their Neuroprotective Effect
title_full Two Cerebrosides Isolated from the Seeds of Sterculia lychnophora and Their Neuroprotective Effect
title_fullStr Two Cerebrosides Isolated from the Seeds of Sterculia lychnophora and Their Neuroprotective Effect
title_full_unstemmed Two Cerebrosides Isolated from the Seeds of Sterculia lychnophora and Their Neuroprotective Effect
title_sort two cerebrosides isolated from the seeds of sterculia lychnophora and their neuroprotective effect
publisher MDPI AG
series Molecules
issn 1420-3049
publishDate 2013-01-01
description Two cerebrosides named 1-O-b-D-glucopyranosyl-(2S,3R,4E,8Z)-2-[(2-hydroxyoctadecanoyl)amido]-4,8-octadecadiene-1,3-diol (1) and soya-cerebroside I (2) were isolated from the seeds of Sterculia lychnophora for the first time. Their structures were completely characterized by spectroscopic methods including IR, MS and NMR. Compound 1 exhibited moderate neuroprotective effect against SH-SY5Y cell damage induced by hydrogen peroxide.
topic Sterculia lychnophora
constituents
cerebrosides
neuroprotective effect
url http://www.mdpi.com/1420-3049/18/1/1181
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AT xiuwenwu twocerebrosidesisolatedfromtheseedsofsterculialychnophoraandtheirneuroprotectiveeffect
AT rufengwang twocerebrosidesisolatedfromtheseedsofsterculialychnophoraandtheirneuroprotectiveeffect
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