Two Cerebrosides Isolated from the Seeds of Sterculia lychnophora and Their Neuroprotective Effect
Two cerebrosides named 1-O-b-D-glucopyranosyl-(2S,3R,4E,8Z)-2-[(2-hydroxyoctadecanoyl)amido]-4,8-octadecadiene-1,3-diol (1) and soya-cerebroside I (2) were isolated from the seeds of Sterculia lychnophora for the first time. Their structures were completely characterized by spectroscopic methods inc...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2013-01-01
|
Series: | Molecules |
Subjects: | |
Online Access: | http://www.mdpi.com/1420-3049/18/1/1181 |
id |
doaj-ce793405157e4e009cfb9dda8dc73f92 |
---|---|
record_format |
Article |
spelling |
doaj-ce793405157e4e009cfb9dda8dc73f922020-11-24T23:40:51ZengMDPI AGMolecules1420-30492013-01-011811181118710.3390/molecules18011181Two Cerebrosides Isolated from the Seeds of Sterculia lychnophora and Their Neuroprotective EffectDi GengXiu-Wen WuRu-Feng WangTwo cerebrosides named 1-O-b-D-glucopyranosyl-(2S,3R,4E,8Z)-2-[(2-hydroxyoctadecanoyl)amido]-4,8-octadecadiene-1,3-diol (1) and soya-cerebroside I (2) were isolated from the seeds of Sterculia lychnophora for the first time. Their structures were completely characterized by spectroscopic methods including IR, MS and NMR. Compound 1 exhibited moderate neuroprotective effect against SH-SY5Y cell damage induced by hydrogen peroxide.http://www.mdpi.com/1420-3049/18/1/1181Sterculia lychnophoraconstituentscerebrosidesneuroprotective effect |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Di Geng Xiu-Wen Wu Ru-Feng Wang |
spellingShingle |
Di Geng Xiu-Wen Wu Ru-Feng Wang Two Cerebrosides Isolated from the Seeds of Sterculia lychnophora and Their Neuroprotective Effect Molecules Sterculia lychnophora constituents cerebrosides neuroprotective effect |
author_facet |
Di Geng Xiu-Wen Wu Ru-Feng Wang |
author_sort |
Di Geng |
title |
Two Cerebrosides Isolated from the Seeds of Sterculia lychnophora and Their Neuroprotective Effect |
title_short |
Two Cerebrosides Isolated from the Seeds of Sterculia lychnophora and Their Neuroprotective Effect |
title_full |
Two Cerebrosides Isolated from the Seeds of Sterculia lychnophora and Their Neuroprotective Effect |
title_fullStr |
Two Cerebrosides Isolated from the Seeds of Sterculia lychnophora and Their Neuroprotective Effect |
title_full_unstemmed |
Two Cerebrosides Isolated from the Seeds of Sterculia lychnophora and Their Neuroprotective Effect |
title_sort |
two cerebrosides isolated from the seeds of sterculia lychnophora and their neuroprotective effect |
publisher |
MDPI AG |
series |
Molecules |
issn |
1420-3049 |
publishDate |
2013-01-01 |
description |
Two cerebrosides named 1-O-b-D-glucopyranosyl-(2S,3R,4E,8Z)-2-[(2-hydroxyoctadecanoyl)amido]-4,8-octadecadiene-1,3-diol (1) and soya-cerebroside I (2) were isolated from the seeds of Sterculia lychnophora for the first time. Their structures were completely characterized by spectroscopic methods including IR, MS and NMR. Compound 1 exhibited moderate neuroprotective effect against SH-SY5Y cell damage induced by hydrogen peroxide. |
topic |
Sterculia lychnophora constituents cerebrosides neuroprotective effect |
url |
http://www.mdpi.com/1420-3049/18/1/1181 |
work_keys_str_mv |
AT digeng twocerebrosidesisolatedfromtheseedsofsterculialychnophoraandtheirneuroprotectiveeffect AT xiuwenwu twocerebrosidesisolatedfromtheseedsofsterculialychnophoraandtheirneuroprotectiveeffect AT rufengwang twocerebrosidesisolatedfromtheseedsofsterculialychnophoraandtheirneuroprotectiveeffect |
_version_ |
1725508849017815040 |