Unique epitopes recognized by antibodies induced in Chikungunya virus-infected non-human primates: implications for the study of immunopathology and vaccine development.

Chikungunya virus (CHIKV) is an Alphavirus that causes chronic and incapacitating arthralgia in humans. Although patient cohort studies have shown the production of CHIKV specific antibodies, the fine specificity of the antibody response against CHIKV is not completely defined. The macaque model of...

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Bibliographic Details
Main Authors: Yiu-Wing Kam, Wendy W L Lee, Diane Simarmata, Roger Le Grand, Hugues Tolou, Andres Merits, Pierre Roques, Lisa F P Ng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24755730/pdf/?tool=EBI