Effect of 2-Hydroxypropyl-β-cyclodextrin on Solubility of Sparingly Soluble Drug Derivatives of Anthranilic Acid

Effect of 2-Hydroxypropyl-β-cyclodextrin on Solubility of Sparingly Soluble Drug Derivatives of Anthranilic Acid

Guest-host complex formation of three drug derivatives of anthranilic acid, mefenamic acid, niflumic acid, and flufenamic acid with 2-hydroxypropyl-β-cyclodextrin (2HP-β-CD) in aqueous solutions was investigated using “Phase solubility study” with UV-vis spectrophotometry. Solubility of sparingly so...

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Bibliographic Details
Main Authors:	Aneta Pobudkowska, Aleksandra Pelczarska, Urszula Domańska
Format:	Article
Language:	English
Published:	MDPI AG 2011-04-01
Series:	International Journal of Molecular Sciences
Subjects:	experimental solubility 2-hydroxypropyl-β-cyclodextrin solubility enhancement thermodynamics of complex formation
Online Access:	http://www.mdpi.com/1422-0067/12/4/2383/

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