Celecoxib, indomethacin and ibuprofen prevent 6-hydroxydopamine-induced PC12 cell death through the inhibition of NFκB and SAPK/JNK pathways

Celecoxib, indomethacin and ibuprofen prevent 6-hydroxydopamine-induced PC12 cell death through the inhibition of NFκB and SAPK/JNK pathways

Objective(s): The possible action of nonsteroidal anti-inflammatory drugs (NSAIDs) in the reduction of reactive oxygen species (ROS) and also as anti-apoptotic agents may suggest them as putative agents for the treatment of neurodegenerative diseases. This study was designed to explore some pathways...

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Bibliographic Details
Main Authors:	Elham Ramazani, Zahra Tayarani-Najaran, Masoud Fereidoni
Format:	Article
Language:	English
Published:	Mashhad University of Medical Sciences 2019-05-01
Series:	Iranian Journal of Basic Medical Sciences
Subjects:	Apoptosis Glutathione NSAIDs Parkinson's disease PC12 cells ROS
Online Access:	http://ijbms.mums.ac.ir/article_12272_568c010006dddb1adbef86668d02505a.pdf

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