Soyasaponins from Zolfino bean as aldose reductase differential inhibitors

Soyasaponins from Zolfino bean as aldose reductase differential inhibitors

Seven triterpenoid saponins were identified in methanolic extracts of seeds of the Zolfino bean landrace (Phaseolus vulgaris L.) by HPLC fractionation, revealing their ability to inhibit highly purified human recombinant aldose reductase (hAKR1B1). Six of these compounds were associated by MS analys...

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Bibliographic Details
Main Authors: Francesco Balestri, Marinella De Leo, Carlo Sorce, Mario Cappiello, Luca Quattrini, Roberta Moschini, Carlotta Pineschi, Alessandra Braca, Concettina La Motta, Federico Da Settimo, Antonella Del-Corso, Umberto Mura
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:
saponins
aldose reductase
differential inhibitors
zolfino bean
phaseolus vulgaris
Online Access:http://dx.doi.org/10.1080/14756366.2018.1553166

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