Structure-guided engineering of a Thermobifida fusca cutinase for enhanced hydrolysis on natural polyester substrate

Structure-guided engineering of a Thermobifida fusca cutinase for enhanced hydrolysis on natural polyester substrate

Abstract Cutinases could degrade insoluble polyester, including natural cutin and synthetic plastic. However, their turnover efficiency for polyester remains too low for industrial application. Herein, we report the 1.54-Å resolution X-ray crystal structure of a cutinase from Thermobifida fusca and...

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Bibliographic Details
Main Authors: Qilei Dong, Shuguang Yuan, Lian Wu, Lingqia Su, Qiaoling Zhao, Jing Wu, Weixue Huang, Jiahai Zhou
Format: Article
Language:English
Published: SpringerOpen 2020-07-01
Series:Bioresources and Bioprocessing
Subjects:
Cutinase
Polyester cutin
Enzyme engineering
Cotton scouring
Loop flexibility
Online Access:http://link.springer.com/article/10.1186/s40643-020-00324-8

Internet

http://link.springer.com/article/10.1186/s40643-020-00324-8

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