Macrophage Polarization in Leprosy–HIV Co-infected Patients

Macrophage Polarization in Leprosy–HIV Co-infected Patients

In HIV-infected individuals, a paradoxical clinical deterioration may occur in preexisting leprosy when highly active antiretroviral therapy (HAART)-associated reversal reaction (RR) develops. Leprosy–HIV co-infected patients during HAART may present a more severe form of the disease (RR/HIV), but t...

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Main Authors: Tatiana Pereira da Silva, Tamiris Lameira Bittencourt, Ariane Leite de Oliveira, Rhana Berto da Silva Prata, Vinicius Menezes, Helen Ferreira, José Augusto da Costa Nery, Eliane Barbosa de Oliveira, Gilberto Marcelo Sperandio da Silva, Euzenir Nunes Sarno, Roberta Olmo Pinheiro
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Immunology
Subjects:
leprosy
HIV-1
monocyte subsets
macrophage phenotype
co-infection
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01493/full

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