Disparity of human immunodeficiency virus incidence and drug resistance in college student, non-student youth and older men who have sex with men: a cross-sectional study from seven major cities of China
Abstract. Background:. Human immunodeficiency virus (HIV) prevalence among student men who have sex with men (MSM) in college is more than 5.0% and keeps on increasing in China. This study aims to clarify the proportion of HIV recent infection, its propeller and the source among college student MSM....
Main Authors: | , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wolters Kluwer
2020-12-01
|
Series: | Chinese Medical Journal |
Online Access: | http://journals.lww.com/10.1097/CM9.0000000000001161 |
id |
doaj-cee565a40abd4982822fc26c68f5b311 |
---|---|
record_format |
Article |
spelling |
doaj-cee565a40abd4982822fc26c68f5b3112020-12-23T08:13:35ZengWolters KluwerChinese Medical Journal0366-69992542-56412020-12-01133232778278610.1097/CM9.0000000000001161202012050-00003Disparity of human immunodeficiency virus incidence and drug resistance in college student, non-student youth and older men who have sex with men: a cross-sectional study from seven major cities of ChinaJing ZhangJun-Jie XuZhen-Xing ChuQing-Hai HuXiao-Xu HanBin ZhaoYong-Jun JiangWen-Qing GengHong ShangNing-Ning Wang.Abstract. Background:. Human immunodeficiency virus (HIV) prevalence among student men who have sex with men (MSM) in college is more than 5.0% and keeps on increasing in China. This study aims to clarify the proportion of HIV recent infection, its propeller and the source among college student MSM. Methods:. We conducted a multicenter cross-sectional study in seven major Chinese cities during 2012-2013. HIV recent infections (≤ 168 days) and incidence was measured and estimated by BED HIV-1 capture enzyme immunoassay (BED-CEIA) testing strategy. HIV-related behaviors and transmitted drug resistance (TDR) were investigated and compared between the college student MSM, <25-year-old non-student youth MSM (NSYM), and ≥25-year-old non-student non-youth MSM (NSNYM), using structured survey, and analyses of drug resistance. Results:. Overall, 4,496 (4496/4526, 99.3%) were eligible for enrollment, comprising 565 college student MSM, 1,094 NSYM, and 2,837 NSNYM. The proportion of HIV recent infection were 70.3% (26/37), 50.8% (65/128) and 35.1% (95/271), the HIV incidence rate were 10.0 (95% CI: 6.2-13.9)/100PY, 12.9 (95% CI: 9.8-16.1)/100PY, 6.8 (95% CI: 5.4-8.2)/100PY, and TDR prevalence were 7.4% (2/27), 2.0%, (2/98) and 4.9% (11/226), among student MSM, NSYM, and NSNYM, respectively. Among HIV positive student MSM with age< 21-year-old, the proportion of HIV recent infection is 90.9% (10/11). Factors independently associated with HIV recent infection in student MSM was usage of recreational drug in the past 6 months (AOR: 2.5; 95% CI: 1.0–5.8). Conclusions:. College student MSM had higher proportion of HIV recent infection and TDR than the youth and older MSM in China during 2012-2013. The HIV infections were more likely to happen during the early year of college life among student MSM.http://journals.lww.com/10.1097/CM9.0000000000001161 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jing Zhang Jun-Jie Xu Zhen-Xing Chu Qing-Hai Hu Xiao-Xu Han Bin Zhao Yong-Jun Jiang Wen-Qing Geng Hong Shang Ning-Ning Wang. |
spellingShingle |
Jing Zhang Jun-Jie Xu Zhen-Xing Chu Qing-Hai Hu Xiao-Xu Han Bin Zhao Yong-Jun Jiang Wen-Qing Geng Hong Shang Ning-Ning Wang. Disparity of human immunodeficiency virus incidence and drug resistance in college student, non-student youth and older men who have sex with men: a cross-sectional study from seven major cities of China Chinese Medical Journal |
author_facet |
Jing Zhang Jun-Jie Xu Zhen-Xing Chu Qing-Hai Hu Xiao-Xu Han Bin Zhao Yong-Jun Jiang Wen-Qing Geng Hong Shang Ning-Ning Wang. |
author_sort |
Jing Zhang |
title |
Disparity of human immunodeficiency virus incidence and drug resistance in college student, non-student youth and older men who have sex with men: a cross-sectional study from seven major cities of China |
title_short |
Disparity of human immunodeficiency virus incidence and drug resistance in college student, non-student youth and older men who have sex with men: a cross-sectional study from seven major cities of China |
title_full |
Disparity of human immunodeficiency virus incidence and drug resistance in college student, non-student youth and older men who have sex with men: a cross-sectional study from seven major cities of China |
title_fullStr |
Disparity of human immunodeficiency virus incidence and drug resistance in college student, non-student youth and older men who have sex with men: a cross-sectional study from seven major cities of China |
title_full_unstemmed |
Disparity of human immunodeficiency virus incidence and drug resistance in college student, non-student youth and older men who have sex with men: a cross-sectional study from seven major cities of China |
title_sort |
disparity of human immunodeficiency virus incidence and drug resistance in college student, non-student youth and older men who have sex with men: a cross-sectional study from seven major cities of china |
publisher |
Wolters Kluwer |
series |
Chinese Medical Journal |
issn |
0366-6999 2542-5641 |
publishDate |
2020-12-01 |
description |
Abstract. Background:. Human immunodeficiency virus (HIV) prevalence among student men who have sex with men (MSM) in college is more than 5.0% and keeps on increasing in China. This study aims to clarify the proportion of HIV recent infection, its propeller and the source among college student MSM.
Methods:. We conducted a multicenter cross-sectional study in seven major Chinese cities during 2012-2013. HIV recent infections (≤ 168 days) and incidence was measured and estimated by BED HIV-1 capture enzyme immunoassay (BED-CEIA) testing strategy. HIV-related behaviors and transmitted drug resistance (TDR) were investigated and compared between the college student MSM, <25-year-old non-student youth MSM (NSYM), and ≥25-year-old non-student non-youth MSM (NSNYM), using structured survey, and analyses of drug resistance.
Results:. Overall, 4,496 (4496/4526, 99.3%) were eligible for enrollment, comprising 565 college student MSM, 1,094 NSYM, and 2,837 NSNYM. The proportion of HIV recent infection were 70.3% (26/37), 50.8% (65/128) and 35.1% (95/271), the HIV incidence rate were 10.0 (95% CI: 6.2-13.9)/100PY, 12.9 (95% CI: 9.8-16.1)/100PY, 6.8 (95% CI: 5.4-8.2)/100PY, and TDR prevalence were 7.4% (2/27), 2.0%, (2/98) and 4.9% (11/226), among student MSM, NSYM, and NSNYM, respectively. Among HIV positive student MSM with age< 21-year-old, the proportion of HIV recent infection is 90.9% (10/11). Factors independently associated with HIV recent infection in student MSM was usage of recreational drug in the past 6 months (AOR: 2.5; 95% CI: 1.0–5.8).
Conclusions:. College student MSM had higher proportion of HIV recent infection and TDR than the youth and older MSM in China during 2012-2013. The HIV infections were more likely to happen during the early year of college life among student MSM. |
url |
http://journals.lww.com/10.1097/CM9.0000000000001161 |
work_keys_str_mv |
AT jingzhang disparityofhumanimmunodeficiencyvirusincidenceanddrugresistanceincollegestudentnonstudentyouthandoldermenwhohavesexwithmenacrosssectionalstudyfromsevenmajorcitiesofchina AT junjiexu disparityofhumanimmunodeficiencyvirusincidenceanddrugresistanceincollegestudentnonstudentyouthandoldermenwhohavesexwithmenacrosssectionalstudyfromsevenmajorcitiesofchina AT zhenxingchu disparityofhumanimmunodeficiencyvirusincidenceanddrugresistanceincollegestudentnonstudentyouthandoldermenwhohavesexwithmenacrosssectionalstudyfromsevenmajorcitiesofchina AT qinghaihu disparityofhumanimmunodeficiencyvirusincidenceanddrugresistanceincollegestudentnonstudentyouthandoldermenwhohavesexwithmenacrosssectionalstudyfromsevenmajorcitiesofchina AT xiaoxuhan disparityofhumanimmunodeficiencyvirusincidenceanddrugresistanceincollegestudentnonstudentyouthandoldermenwhohavesexwithmenacrosssectionalstudyfromsevenmajorcitiesofchina AT binzhao disparityofhumanimmunodeficiencyvirusincidenceanddrugresistanceincollegestudentnonstudentyouthandoldermenwhohavesexwithmenacrosssectionalstudyfromsevenmajorcitiesofchina AT yongjunjiang disparityofhumanimmunodeficiencyvirusincidenceanddrugresistanceincollegestudentnonstudentyouthandoldermenwhohavesexwithmenacrosssectionalstudyfromsevenmajorcitiesofchina AT wenqinggeng disparityofhumanimmunodeficiencyvirusincidenceanddrugresistanceincollegestudentnonstudentyouthandoldermenwhohavesexwithmenacrosssectionalstudyfromsevenmajorcitiesofchina AT hongshang disparityofhumanimmunodeficiencyvirusincidenceanddrugresistanceincollegestudentnonstudentyouthandoldermenwhohavesexwithmenacrosssectionalstudyfromsevenmajorcitiesofchina AT ningningwang disparityofhumanimmunodeficiencyvirusincidenceanddrugresistanceincollegestudentnonstudentyouthandoldermenwhohavesexwithmenacrosssectionalstudyfromsevenmajorcitiesofchina |
_version_ |
1724372947665158144 |