The effect of diet therapy on the anthropometric and metabolic parameters in women with infertility and obesity
Aim: to monitor the anthropometric, hormonal and metabolic parameters in women of reproductive age with infertility and grade I gluteofemoral obesity during treatment with a balanced hypocaloric diet.Materials and methods. The study included 23 infertile women of reproductive age. All patients were...
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doaj-cf176c788ccc4e8aaa20a98e465df52f2021-07-28T13:44:41ZrusIRBIS LLCАкушерство, гинекология и репродукция2313-73472500-31942020-04-0114171410.17749/2313-7347.2020.14.1.7-14532The effect of diet therapy on the anthropometric and metabolic parameters in women with infertility and obesityN. V. Artymuk0O. A. Tachkova1N. A. Sukhova2Kemerovo State Medical University, Health Ministry of Russian FederationKemerovo State Medical University, Health Ministry of Russian FederationKemerovo State Medical University, Health Ministry of Russian FederationAim: to monitor the anthropometric, hormonal and metabolic parameters in women of reproductive age with infertility and grade I gluteofemoral obesity during treatment with a balanced hypocaloric diet.Materials and methods. The study included 23 infertile women of reproductive age. All patients were prescribed a balanced, low-calorie diet (1200 kcal/day), exercise, and behavioral therapy. The anthropometric, metabolic and hormonal parameters were determined before and 12 months after the treatment. We measured the levels of leptin, total cholesterol, triglycerides, triglycerides, high-density and low-density lipoprotein cholesterol (HDL cholesterol and LDL cholesterol), fasting glycose. Following the measurements, the atherogenic and insulin resistance indices were calculated. In addition, the plasma concentrations of luteinizing hormone, follicle-stimulating hormone, prolactin, estrone, estradiol, testosterone, progesterone, and immunoreactive insulin were measured.Results. Twenty patients completed the study. A decrease in body weight (by average of 10.58 ± 5.70 kg) was found in 87 % of patients; in parallel, the body mass index decreased from 32.53 ± 1.40 to 28.55 ± 2.50 kg/m2 (p < 0.001). The decrease in body weight was accompanied by a statistically significant decrease in the levels of leptin (p < 0.001), estrone (p = 0.049), estradiol (p = 0.032), total cholesterol (p < 0.001), triglycerides (p = 0.004), LDL cholesterol (p = 0.001), fasting glycose (p < 0.001), insulin resistance index (p = 0.002), atherogenic index (p < 0.001) and an increase in the level of progesterone (p = 0.030). The ovulatory menstrual cycle was restored in all women (p = 0.007); within one year, wanted pregnancy occurred in 1 woman.Conclusion. The use of a low-calorie diet for 12 months in infertile women with grade I gluteofemoral obesity leads to normalization of metabolic parameters, weight loss and, the restoration of the ovulatory menstrual cycle in 100 % of cases.https://www.gynecology.su/jour/article/view/620obesityreproductive ageinfertilitydiet therapy |
collection |
DOAJ |
language |
Russian |
format |
Article |
sources |
DOAJ |
author |
N. V. Artymuk O. A. Tachkova N. A. Sukhova |
spellingShingle |
N. V. Artymuk O. A. Tachkova N. A. Sukhova The effect of diet therapy on the anthropometric and metabolic parameters in women with infertility and obesity Акушерство, гинекология и репродукция obesity reproductive age infertility diet therapy |
author_facet |
N. V. Artymuk O. A. Tachkova N. A. Sukhova |
author_sort |
N. V. Artymuk |
title |
The effect of diet therapy on the anthropometric and metabolic parameters in women with infertility and obesity |
title_short |
The effect of diet therapy on the anthropometric and metabolic parameters in women with infertility and obesity |
title_full |
The effect of diet therapy on the anthropometric and metabolic parameters in women with infertility and obesity |
title_fullStr |
The effect of diet therapy on the anthropometric and metabolic parameters in women with infertility and obesity |
title_full_unstemmed |
The effect of diet therapy on the anthropometric and metabolic parameters in women with infertility and obesity |
title_sort |
effect of diet therapy on the anthropometric and metabolic parameters in women with infertility and obesity |
publisher |
IRBIS LLC |
series |
Акушерство, гинекология и репродукция |
issn |
2313-7347 2500-3194 |
publishDate |
2020-04-01 |
description |
Aim: to monitor the anthropometric, hormonal and metabolic parameters in women of reproductive age with infertility and grade I gluteofemoral obesity during treatment with a balanced hypocaloric diet.Materials and methods. The study included 23 infertile women of reproductive age. All patients were prescribed a balanced, low-calorie diet (1200 kcal/day), exercise, and behavioral therapy. The anthropometric, metabolic and hormonal parameters were determined before and 12 months after the treatment. We measured the levels of leptin, total cholesterol, triglycerides, triglycerides, high-density and low-density lipoprotein cholesterol (HDL cholesterol and LDL cholesterol), fasting glycose. Following the measurements, the atherogenic and insulin resistance indices were calculated. In addition, the plasma concentrations of luteinizing hormone, follicle-stimulating hormone, prolactin, estrone, estradiol, testosterone, progesterone, and immunoreactive insulin were measured.Results. Twenty patients completed the study. A decrease in body weight (by average of 10.58 ± 5.70 kg) was found in 87 % of patients; in parallel, the body mass index decreased from 32.53 ± 1.40 to 28.55 ± 2.50 kg/m2 (p < 0.001). The decrease in body weight was accompanied by a statistically significant decrease in the levels of leptin (p < 0.001), estrone (p = 0.049), estradiol (p = 0.032), total cholesterol (p < 0.001), triglycerides (p = 0.004), LDL cholesterol (p = 0.001), fasting glycose (p < 0.001), insulin resistance index (p = 0.002), atherogenic index (p < 0.001) and an increase in the level of progesterone (p = 0.030). The ovulatory menstrual cycle was restored in all women (p = 0.007); within one year, wanted pregnancy occurred in 1 woman.Conclusion. The use of a low-calorie diet for 12 months in infertile women with grade I gluteofemoral obesity leads to normalization of metabolic parameters, weight loss and, the restoration of the ovulatory menstrual cycle in 100 % of cases. |
topic |
obesity reproductive age infertility diet therapy |
url |
https://www.gynecology.su/jour/article/view/620 |
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