Forward Genetic Dissection of Biofilm Development by Fusobacterium nucleatum: Novel Functions of Cell Division Proteins FtsX and EnvC

Fusobacterium nucleatum is a key member of the human oral biofilm. It is also implicated in preterm birth and colorectal cancer. To facilitate basic studies of fusobacterial virulence, we describe here a versatile transposon mutagenesis procedure and a pilot screen for mutants defective in biofilm f...

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Bibliographic Details
Main Authors: Chenggang Wu, Abu Amar Mohamed Al Mamun, Truc Thanh Luong, Bo Hu, Jianhua Gu, Ju Huck Lee, Melissa D’Amore, Asis Das, Hung Ton-That, Hui Wu, Marvin Whiteley
Format: Article
Language:English
Published: American Society for Microbiology 2018-04-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/9/2/e00360-18