Next generation sequencing analysis of human platelet PolyA+ mRNAs and rRNA-depleted total RNA.

BACKGROUND: Platelets are small anucleate cells circulating in the blood vessels where they play a key role in hemostasis and thrombosis. Here, we compared platelet RNA-Seq results obtained from polyA+ mRNA and rRNA-depleted total RNA. MATERIALS AND METHODS: We used purified, CD45 depleted, human bl...

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Bibliographic Details
Main Authors: Antheia Kissopoulou, Jon Jonasson, Tomas L Lindahl, Abdimajid Osman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3859545?pdf=render