CD133 mRNA-transfected dendritic cells induce coordinated cytotoxic and helper T cell responses against breast cancer stem cells
Breast cancer, a leading cause of death yearly, has been shown to be initiated and propagated by cancer stem cells. CD133, a cell surface antigen, has been shown to be present on cancer stem cells of many solid tumors, including breast cancer. A limitation to targeting CD133 is major histocompatibil...
Main Authors: | Angelique Sao-Mai Sy Tay, Takayuki Amano, Lincoln A. Edwards, John S. Yu |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-09-01
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Series: | Molecular Therapy: Oncolytics |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2372770521000723 |
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