Detection of Urothelial Bladder Cancer Based on Urine and Tissue Telomerase Activity Measured by Novel RT-TRAP-2PCR Method

Detection of Urothelial Bladder Cancer Based on Urine and Tissue Telomerase Activity Measured by Novel RT-TRAP-2PCR Method

Purpose: To assess the diagnostic performance of urine telomerase activity (TA) in detecting bladder cancer (BCa) using the modified Telomeric Repeat Amplification Protocol (TRAP) and the Real Time Telomeric Repeat Amplification Protocol with double Polymerase Chain Reaction (RT-TRAP-2PCR). Methods:...

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Bibliographic Details
Main Authors: Alexander Glukhov, Natalya Potoldykova, Mark Taratkin, Sergey Gordeev, Konstantin Polyakovsky, Ekaterina Laukhtina, Marco Moschini, Mohammad Abufaraj, Shahrokh F. Shariat, Marina Sekacheva, Dmitry Enikeev, Petr Glybochko
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Journal of Clinical Medicine
Subjects:
bladder cancer
non-invasive diagnosis of bladder cancer
urine biomarker
RT-TRAP-2PCR
non-isotopic TRAP assay
Online Access:https://www.mdpi.com/2077-0383/10/5/1055

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